OBJECTIVE To review the diagnosis and management of drug overdosage in a two-part presentation. DATA SOURCES A review of articles reported on drug overdose and poisoning. SUMMARY OF REVIEW A patient who has taken an overdose of a common drug often presents with an alteration in neurological, cardiovascular and respiratory functions. The differential diagnosis includes, central nervous syste...

The effects of simulated heat waves on body weight, body temperature, and biomarkers of cardiac function in ApoE-/- mice were investigated. Heat waves were simulated in a meteorological environment simulation chamber according to data from a heat wave that occurred in July 2001 in Nanjing, China. Eighteen ApoE-/- mice were divided into control group, heat wave group, and heat wave BH4 group. Mi...

Background Aspiration pneumonitis is characterized by proteinaceous pulmonary edema and acute infiltration of neutrophils into the alveolar space. This study examined the role of the proinflammatory cytokhe, tumor necrosis factor-a (TNFa), on the pathogenesis of the injury produced by the different components that may be present in the aspirate, acid, or gastric particles. Methods: Rats were in...

OBJECTIVE To study protection effect of Xuanfudaizhetang on reflux esophagitis in rats. METHODS A total of 50 Wistar rats were randomly divided into groups A, B, C, D and E with 10 in each. Reflux esophagitis model in rats was established by incomplete helicobacter seam+lower esophagus sphincterotomy. All rats were divided into 5 groups: group A as control group, group B as model group, group...

OBJECTIVE The objective of this study was to evaluate the relationship between histological chorioamnionitis and laboratory markers of infection and congenital sepsis in very-low-birth-weight (VLBW) premature neonates. METHOD This study is a retrospective review of laboratory results of VLBW neonates with birth weight less than 1500 g in our neonatal intensive care unit (NICU) in the last 5 y...

Poisoning is a common preventable cause of morbidity and mortality in children. Most of the poisoning in children less than 5 years of age is accidental. Objective of the study was to study the clinical profile and outcome of childhood poisoning and intoxication. This was a retrospective study done in patients who were admitted in pediatric wards and pediatric intensive care unit (PICU) of BP K...

Twenty cases of ALP poisoning aged between 7-12 years who were admitted in the Pediatric Emergency Services between July 1995 to July 1996 were evaluated. The diagnosis was made on the basis of the history of ingestion and positive silver nitrate tests on gastric lavage fluid. All routine investigations including, serum electrolytes, liver function tests, renal function tests, acid blood gas an...

Background: the national and international guidelines of the WHO and the IUALTD recommend priority sputum smears for diagnosis of pulmonary tuberculosis. We studied the use and diagnostic yield of sputum, broncho-alveolar and gastric lavage (BAL, GL) in the reference national mycobacteria Laboratory (NRL) (Burkina Faso) to see if clinicians follow the recommendations in the prescription of spec...

Abstract Background The optimal treatment in patients with gastric cancer and peritoneal disease remains controversial. Some guidelines indicate palliative only, while others consider surgical case of positive lavage cytology (CY+) or limited disease. Here, we analyzed the role cancer, prognostic relevance response to neoadjuvant therapy. Methods In this retrospective cohort analysis, adenocarc...