We have developed a reconstituted gel-sol and contractile model system that mimics the structure and dynamics found at the ectoplasm/endoplasm interface in the tails of many amoeboid cells. We tested the role of gel-sol transformations of the actin-based cytoskeleton in the regulation of contraction and in the generation of endoplasm from ectoplasm. In a model system with fully phosphorylated m...

Cement-based concrete is the most widely used building and construction material in the world. Although concrete itself is relatively durable when used under the mild environments, its intrinsic weak tensile strength greatly limits its application due to its porous structure. Traditional strategies to overcome this weakness of concrete include utilization of various reinforcing materials, such ...

The present investigation was aimed to formulate and characterize ion-activated in-situ gel loaded with Rizatriptan Benzoate (RIZ) for intranasal administration brain targeting. further optimized process formulation parameters by using 32 factorial design. batch having the concentrations of gellan gum HPMC E15 LV 33.83 mg 9.6 respectively. Gel strength mucoadhesive were found be 32.54 sec 2580....

Corneal ulcer, which is brought on by a breach in the epithelial barrier, dangerous infection of avascular corneal stroma. New treatment strategies are needed, suppressing aggressive nature disease and including combination different drugs. In this study, vancomycin (VAN) fluconazole (FLU) dual-drug loaded dual-layered polyvinyl alcohol gelatin (PVA/GEL) nanofibrous patches produced electrospin...

nanocrystalline zro2 with particle size of about 38 nm was directly synthesized by sol-gel auto-combustion method. the overall process involved three steps: formation of homogeneous sol at 50-55°c; formation of dried gel at 110°c, and combustion of the dried gel at 400°c. experiments revealed that zro2 dried gel derived from glycine (fuel) and nitrate sol exhibited self propagating combustion a...