Rhinoscleroma is a chronic, infectious and granulomatous disease of the respiratory tract. There is often a delay in diagnosis due to unfamiliarity with the disease and also because culture is not always positive. We report a case in a 26-year-old woman with granular mass obstructing bilateral nasal cavities and causing breathing difficulty. Histopathological examination showed characteristic M...

Nuclear medicine imaging has been used to localize infection sites and efforts have been continued to develop modified infection specific radiopharmaceuticals. In this study gemifloxacin as a broad-spectrum quinolone has been labeled with [99mTc (CO)3 (H2O)3]+ core in order to evaluate its feasibility as an infection imaging agent for in vivo use. The stability of radioconjugate was checked in ...

Introduction Fluoroquinolones have demonstrated comparable efficacy and rates of adverse events as β-lactam and/or macrolide agents in the treatment of community-acquired and healthcare-associated infections. Fluoroquinolones currently marketed are generally considered to have good safety profiles (1–5). However, post-marketing spontaneous adverse event reports have imposed updates in the preca...