Drought causes an increase in some gene expression in plant tissues such as plasma membrane intrinsic proteins type 1 (PIP1), 9-cis-epoxycarotenoid dioxygenase (NCED) SlAREB1. The effects of exogenous abscisic acid (ABA) and two sulfonamide compounds, namely, sulfacetamide (Sa) and sulfasalazine (SS) were studied on gene expression of tomato (Lycopersicon esculentum Mill. Cv. Super chief) under...

Molecular information of K+ accumulation in grapes is strongly required. Under salinity condition potassium transporters are inhibited by Na+. The aim of this study was to investigate the effects of salinity on the expression of K+ transporter genes in grape. Based on the previous screening study on 18 grape genotypes, ‘H6’ and ‘Gharashani’ (tolerant) and ‘Shirazi’ and ‘GhezelUzum’ (sensitive) ...

background : the study was aimed to show the effect of molecular mechanism of aqueous garlic extract (age) on expression of ifnγ and inos genes in leishmania major . methods : leishmania major promastigotes (mrho/ir/75/er) were added to the in-vitro cultured j774 cell line, the cells were incubated for 72 hours. various concentrations of garlic extract (9.25, 18.5, 37, 74, 148 mg/ml) were added...

objective(s): the oct4b1, as one of oct4 variants, is expressed in cancer cell lines and tissues more than other variants and plays an important role in apoptosis and stress (heat shock protein) pathways. the present study was designed to determine the effects of oct4b1 silencing on expressional profile of hsp40 gene family expression in three different human tumor cell lines. materials and met...

Background: Microarray experiments can simultaneously determine the expression of thousands of genes. Identification of potential genes from microarray data for diagnosis of cancer is important. This study aimed to identify genes for the diagnosis of acute myeloid and lymphoblastic leukemia using a sparse feature selection method. Materials and Methods: In this descriptive study, the expressio...

esophageal squamous cell carcinoma (escc) is a deadly cancer with poor prognosis. in this regard, early diagnosis is of vital importance to cure the tumor in its early stages. novel cancer diagnostic and therapeutic approaches have been recently introduced based on micrornas (mirnas). also, accurate normalization using appropriate reference genes is a critical step in mirna expression studies. ...

Physiological studies confirm improvement of memory by Olibanum, a resin from Boswellia species, while little is known about the molecular mechanism by which it affects memory performance. Two master transcription factors, CREB-1 and CREB-2, regulate downstream memory-related genes expression, leading to the long-term memory potentiation. This study addresses the effects of Beta-boswellic acid ...

Background: Salivary gland tumors (SGT) are rare lesions with uncertain histopathology. One of the major signaling pathways that participate in the development of several tumors is protein kinase A. In this pathway, glycogen synthase kinase β (GSK3β) and cAMP responsive element binding protein (CREB3) are two genes which are supposed to be down regulated in most human tumors. The expression lev...

background: leishmaniasis is a worldwide disease prevalent in tropical and sub- tropical countries in the world. characterization of inflammatory responses produced in cutaneous leishmaniasis has not yet been completed. methods: the specific primers were designed for ten pro-inflammatory genes including ccl4, ccl3, tnf-α, il-1α, il-12p35, il-12p40, ccl5, ccr5, il-1β and ifn- γ and their express...