introduction social development is a phenomenon having close relationship with ways and how the people live in a society. the main goal of  social development is to upgrade the levels of general livings’ status by creating preferred conditions based on accepted values.focuses must be on: reducing poverty and improving the qualities of nutrition, hygiene, housing, occupation, education and fruit...

Early embryonic growth is independent of pituitary growth hormone (GH), since it occurs prior to the differentiation of pituitary somatotrophs. Embryogenesis is therefore thought to be regulated by local growth factors. As GH is now known to be produced in many extrapituitary sites, in which it acts in an autocrine or paracrine manner, the possibility that extra-pituitary GH may participate in ...

Glucocorticoid (GC) treatment of rat or chicken embryonic pituitary (CEP) cells induces premature production of growth hormone (GH). GC induction of the GH gene requires ongoing protein synthesis, and the GH genes lack a canonical GC response element (GRE). To characterize cis-acting elements and identify trans-acting proteins involved in this process, we characterized the regulation of a lucif...

This paper offers an analysis of the development and institutionalisation of the sociology of health and medicine in Australia. As a former British colony, sociology was primarily brought into the country with its British and European migrants, and developed in a series of six discrete stages: the formative years of the Colonial period and early decades after Federation; the period of inter-dis...

Every discourse has a context. Every discourse has a motive. The Sociology that developed in 19th century France was a response to the social crisis that was experienced there at that time. The Sociology that developed in 19th century France had a context. The man who is considered to be the founding father of Sociology, Auguste Comte was convinced that a science of society was possible and wou...

Recent reform in U.S. school systems has focused on closing racial achievement gaps, but despite great efforts, are children being socially left behind? We know from prior research that adolescents see their relationships with peers, teachers, and parents as defining aspects of their lives and that the absence of these relationships is linked with a host of negative outcomes. Previous work also...

TransCon growth hormone is a sustained-release human growth hormone prodrug under development in which unmodified growth hormone is transiently linked to a carrier molecule. It is intended as an alternative to daily growth hormone in the treatment of growth hormone deficiency. This was a multi-center, randomized, open-label, active-controlled trial designed to compare the safety (including tole...

Locally produced growth hormone (GH) and IGF-I are key factors in the regulation of mammary gland (MG) development and may be important in breast cancer development/progression. Somatostatin (SST) and cortistatin (CORT) regulate GH/IGF-I axis at various levels, but their role in regulating GH/IGF-I in MGs remains unknown. Since obesity alters the expression of these systems in different tissues...

Growth hormone (GH) and IGFs have a long distinguished history in diabetes, with possible participation in the development of renal complications. The implicated effect of GH in diabetic end-stage organ damage may be mediated by growth hormone receptor (GHR) or postreceptor events in GH signal transduction. The present study investigates the effects of diabetes induced by streptozotocin (STZ) o...

Growth hormone (GH)-deficiency is usually associated with elevated adiposity, hyperleptinemia, and increased fracture risk. Since leptin is thought to enhance cortical bone formation, we have investigated the contribution of elevated adiposity and hyperleptinemia on femoral strength in rodent models of GH deficiency. Quantification of the transpubertal development of femoral strength in the mod...