NG2-glia are a substantial population of cells in the central nervous system (CNS) that can be identified by their specific expression of the NG2 chondroitin sulphate (CSPG). NG2-glia can generate oligodendrocytes, but it is unlikely this is their only function; indeed, they may be multipotent neural stem cells. Moreover, NG2-glia are a highly reactive cell type and a major function is to help ...

Cover Illustration: Confocal image of a mature oligodendrocyte in vitro following the addition netrin-1, immuno-labelled for mitochondrial docking protein syntaphilin (red), outer membrane TOM20 (green), myelin basic (white), and Hoechst dye (blue). Syntaphilin is associated with mitochondria oligodendrocytes recruited to cell processes by netrin-1. (See Nakamura, DS, et al. https://doi.org/10....