Abstract In recent years, new properties of space-time duality in the Hamiltonian formalism certain integrable classical field theories have been discovered and led to their reformulation using ideas from covariant theory: this sense, nature r -matrix structure was unravelled. Here, we solve open question extending these results a whole hierarchy. We choose Ablowitz–Kaup–Newell–Segur (AKNS) To ...

BACKGROUND Lymph node stage prior to treatment is strongly related to disease progression and poor prognosis in non-small cell lung cancer (NSCLC). However, few studies have investigated metabolic imaging features derived from pre-radiotherapy 18F-fluorodeoxyglucose (FDG) positron-emission tomography (PET) of metastatic hilar/mediastinal lymph nodes (LNs). We hypothesized that these would provi...

Radiomics has the potential to improve the management of cancer patients, but further research is required before it can be adopted into routine clinical practice.

It is estimated that approximately 22,000 Americans will be diagnosed with tumor of the brain or nervous system in 2010. Among primary brain tumors, approximately 60% are gliomas, the most common and most malignant of which is glioblastoma multiforme (GBM).The DecisionDx-GBM test is a multigene expression assay that is designed to predict which patients are likely to experience long-term (> 2 y...

Glioblastoma multiform (GBM) is a highly malignant brain tumor. Bevacizumab is a recent therapy for stopping tumor growth and even shrinking tumor through inhibition of vascular development (angiogenesis). This paper presents a non-invasive approach based on image analysis of multi-parametric magnetic resonance images (MRI) to predict response of GBM to this treatment. The resulting prediction ...

Glioblastoma is the most common and aggressive type of primary brain tumor in humans. It is located preferentially in the cerebral hemispheres. Glioblastoma arises from complex interactions between a variety of genetic, epigenetic alterations and environmental perturbations. However, the precise mechanism of glioblastoma is unknown and its survival rate is very low. The Cancer Genome Atlas (TCG...

Since the discovery of X-rays at the end of the 19th century, medical imageology has progressed for 100 years, and medical imaging has become an important auxiliary tool for clinical diagnosis. With the launch of the human genome project (HGP) and the development of various high-throughput detection techniques, disease exploration in the post-genome era has extended beyond investigations of str...