We examined the effect of parental folate deficiency on the folate content, global DNA methylation, folate receptor-alpha (FRα), insulin-like-growth factor-2 (IGF-2) and -1 receptor (IGF-1R) in the liver and plasma homocysteine in the postnatal rat. Male and female rats were randomly fed a folic acid-deficient (paternal folate-deficient, PD and maternal folate-deficient, MD), or folic acid-supp...

We compared the temporal variability of the heat content of the world ocean, of the global atmosphere, and of components of Earth's cryosphere during the latter half of the 20th century. Each component has increased its heat content (the atmosphere and the ocean) or exhibited melting (the cryosphere). The estimated increase of observed global ocean heat content (over the depth range from 0 to 3...

In software usability testing, empirical software engineering, or user evaluation, experimenters collect various types of data. Understanding such data requires cognitively intensive qualitative analysis based on the cycle of discovery and validation processes. We need computational tools that are suitable for supporting experimenters to discover important aspects of the data, to collect them, ...

After years of stagnation in the Internet following the burst of the New Economy, a new phenomenon ignites the fantasies of the Internet community. Web 2.0 seems to redefine the economical foundations of the Internet economy. Services such as MySpace, YouTube and Second Life have demonstrated the power of the alleged new online community services. User-generated content and social networks are ...

This article presents results from a study of online presence in activist milieus associated with the radical left in Sweden discussed from a perspective of non-participation. With the aim to further the understanding of digital nonparticipation as communicative strategy in activism, it builds upon empirical findings and argues that the online practices and use of social media, as could be obse...

Thir report presents a study made of the DSN charged particle calibration requirements. The ejyects of charged particles on navigation and timing systems were reviewed and it was prcposed that a system based upon the Global Positioning System satellites be used to measure the charged particle content of the ionosphere. The system would be required to measure the total electron content of the io...

Content-based Image Retrieval (CBIR) has become one of the most active research areas in the past few years. Most of the attention from the research has been focused on indexing techniques based on global feature distributions. However, these global distributions have limited discriminating power because they are unable to capture local image information. Applying global Gabor texture features ...

BACKGROUND Epigenetic programming and epigenetic mechanisms driven by environmental factors are thought to play an important role in human health and ageing. Global DNA methylation has been postulated as an epigenetic marker for epidemiological studies as it is reflective of changes in gene expression linked to disease. How epigenetic mechanisms are affected by psychological, sociological and b...