Immune complex 'lupus-like glomerulonephritis' is a type of renal injury seen infrequently in human immunodeficiency virus (HIV) patients and very little is known about the clinical course and treatment. Treatment options are limited but antiretroviral therapy and steroids have been tried with limited success. We report a case of a 21-year-old HIV-positive African American male with lupus-like ...

Malaria is one of the leading causes of acute renal failure in south-east Asia especially India and Vietnam, and Africa1. Plasmodium vivax is the predominant malarial parasite in India accounting for 50.4– 56.4% cases in the last five years2. Falciparum malaria is the more severe variant of malaria in the region commonly associated with renal complications. Renal manifestations described in fal...

Membranous glomerulonephritis can occur as a rare paraneoplastic complication of human cancers. In this case report, we describe a patient who presented acutely with symptoms of the nephrotic syndrome including heavy proteinuria and anasarca. He was subsequently diagnosed with membranous glomerulonephritis, and soon afterwards was found to have stage IIIB non-small cell lung cancer. Following c...

Introduction: Monoclonal gammopathy of renal significance (MGRS) is described as a hematologic condition characterized by nephrotoxicmonoclonal proteins produced non-malignant B-cell or plasma cell clone. Nevertheless, MGRS can cause serious lesions, leading to high morbidity. In C3 glomerulonephritis, monoclonal protein damage indirectly. Acting an autoantibody, the cannot be detected in kidne...

The prevalence, pathogenesis, predictors, and natural course of patients with recurrent glomerulonephritis (GN) de novo GN occurring after renal transplantation (RT) remains incompletely understood. Consequently, the treatment options was poorly described largely extrapolated from general population. We aimed to determine incidence GN, clinical pathological characteristics these post-transplant...

This chapter will provide a comprehensive review of post-infectious glomerulonephritis focusing in particular on the changing epidemiology and long term outcome. The immunological response of the kidney to an insult results in glomerulonephritis. The insult can result from a large number of conditions, both infectious and non-infectious. Regardless of the initial insult, the outcome is similar ...

We report a case of a 71-year-old man with rapidly progressive nephritic syndrome and dual positivity for anti-glomerular basement membrane antibody and myeloperoxidase-specific anti-neutrophil cytoplasmic antibody. Renal biopsy revealed crescentic, mainly cellular, glomerulonephritis with granulomatous lesions, and advanced membranous changes. Membranous nephropathy had apparently existed for ...

Background & Objectives: Chronicity of lupus nephritis (LN) should be considered for interaction of cell mediated immunity (CMI) and dendritic cells in glomeruli and tubulointerstitial areas. In this study establishment of immunohistopathological changes of dendritic cells and other immune effector cells in lupus nephritis comparing with non-lupus nephritis was performed. Materials & Methods: ...

A quarter of the cardiac output is consigned to the perfusion of the kidneys – even though the kidneys amount to just 0.5 % of the total body weight. Approximately every 20 minutes, i.e. 70 times a day, the entire blood plasma is filtered by the kidneys. Therefore, kidney glomeruli are target organs for every hematogenous infection. Viral infection can cause primary glomerulonephritis, whereas ...

A 43 year old woman who initially presented with the nephrotic syndrome, glomerulonephritis, and antinuclear antibodies (ANAs) was given the diagnosis of systemic lupus erythematosus (SLE). One year later the patient developed progressive subcutaneous nodules on her forearms, with histopathology of non-caseating granulomas. Further evaluation of the patient showed mediastinal lymphadenopathy an...