background: the efficacy of various screening variables in detection of diabetes mellitus (dm) is unclear.   objective: to determine the efficacy of various diagnostic tests for type 2 dm.   methods: 1021 inhabitants of hakimieh district of tehran aged between 30 and 75 years were studied.  known cases of diabetes and those with factors influencing glucose tolerance test were excluded.  age, se...

RESEARCH DESIGN AND METHODSdWe performed a frequently sampled intravenous glucose tolerance test (FSIGT) withminimal model analysis and ameal tolerance test (MTT) in 20 subjects with impaired fasting glucose (11 men, 9 women; mean age 60.76 1.9 years, BMI 29.4 6 0.9 kg/m) in a single-blind study after 2 weeks of placebo treatment and 8 weeks of colesevelam 3.75 g daily. From these tests, insuli...