Objective: The present study was carried out to evaluate the anticancer property of ethanol extract of Scaevola taccada leaves against Ehrlich ascites carcinoma in Swiss albino mice. Materials and Methods: The leaves powder was subjected to continuous hot extraction using ethanol and cold maceration by water to get Ethanol and Aqueous extracts, respectively. Identification of the chemical const...

INTRODUCTION Roots of Ixora coccinea (Rubiaceae), and Rhinacanthus nasuta (Acanthaceae) and whole plants of Spilanthes ciliata (Asteraceae) are extensively used by tribal communities in South India to treat liver diseases. However, the veracity of these tribal claims has not been investigated scientifically using the liver toxin, aflatoxin. This study reports on the protective effects of these ...

SCOPE SlimTrym® is a formulated product composed of citrus polymethoxyflavones (PMFs), green tea extract, and lychee extract. We investigated the effect of dietary SlimTrym® on diet-induced obesity and associated non-alcoholic fatty liver disease (NAFLD) in mice. METHODS AND RESULTS Male C57BL/6 mice were fed a normal diet (ND), high fat diet (HFD) or HFD containing 0.1% or 0.5% SlimTrym® for...

The effect of repeated administration of aqueous extract of Enantia chloranta stem bark on selected enzyme activities of rat liver was investigated. The aqueous extract of the plant was administered to white albino rats daily at 24hr interval at a dosage level of 100mg/kg body weight after which the rats were sacrificed after receiving 1, 3 and 5 daily oral doses. Administration of the extract ...

To examine the effects of N nutrition upon endosperm development, maize (Zea mays) kernels were grown in vitro with either 0, 3.6, 7.1, 14.3, or 35.7 millimolar N. Kernels were harvested at 20 days after pollination for determination of enzyme activities and again at maturity for quantification of storage products and electrophoretic separation of zeins. Endosperm dry weight, starch, zein-N, an...

Homeopathy is considered as one modality for cancer therapy. However, there are only very few clinical reports on the activity of the drugs, as well as in experimental animals. Presently we have evaluated the inhibitory effects of potentized homeopathic preparations against N'-nitrosodiethylamine (NDEA) induced hepatocellular carcinoma in rats as well as 3-methylcholanthrene-induced sarcomas in...

Berberis aristata DC (Berberidaceae) is used in Indian traditional medicine. The hepatoprotective activity of Berberis aristata stem bark suspension was studied using CCl4 overdose induced liver damage in rats. The activity was assessed by monitoring various liver functions testing enzymes viz, Serum Glutamate Pyruvate transaminase (SGPT), Serum Glutamate Oxaloacetate Transaminase (SGOT), Serum...

The aim of this study is to investigate dose dependent antidiabetic and antioxidant effects of aqueous methanol extract of seed of Tamarindus indica Linn on fasting and postprandial blood glucose level, liver and muscle glycogen content, haemoglobin level, glycosylated haemoglobin level, liver hexokinase activity, serum insulin level and on the antioxidant enzymes such as catalase, peroxidase, ...

Oxalis corniculata is well known for its medicinal properties like anti-inflammatory, digestive, diuretic, antibacterial, antiseptic etc. The present study focuses on the ability of O. corniculata to alleviate liver damage caused by over dose of paracetamol. Antioxidant activity of O. corniculata was evaluated using the free radical scavenging activity of 1, 1-diphenyl-2- picrylhydrazyl radical...

Flower extract of C. officinalis L. was evaluated for its protective effect against CCl4 induced acute hepatotoxicity and cisplatin induced nephrotoxicity. The activities of serum marker enzymes of liver injury like glutamate pyruvate transaminase (SGPT), glutamate oxaloacetate transaminase (SGOT) and alkaline phosphatase (ALP) which were increased by CCl4 injection was found to be significantl...