false-positive results in S. pneumoniae cases because only the amount of CDT (a-to di-or trisialotransferrin) and/or the CDT/transferrin ratio is determined (19). HUS associated with S. pneumoniae therefore has to be considered in the diagnosis of primary and secondary defects in the glycan part of N-glycoproteins. The non-S. pneumoniae-associated HUS cases showed normal isoform distribution in...

BACKGROUND Plasma total homocysteine (tHcy) is commonly elevated in persons with diabetes. This may be due to effects of insulin and/or glucose and/or metabolic control on the metabolism or plasma levels of tHcy. This study examined the effects of fasting plasma glucose status on fasting tHcy levels among adults without diabetes, and diabetes per se among adults with a self-report history of di...

diabetes mellitus (dm) type 2 is one of the most common endocrine disorders affecting more than 135 million people in the world. the etiology of the disease is not fully understood, but recently subclinical hemochromatosis has been considered as one of the probable causes of dm. this study was carried out to examine the relationship between serum ferritin as a marker of iron overload with dm an...

UNLABELLED Aims/Introduction:  A method of estimating HbA1c attained after initiation of basal supported oral therapy (BOT) has not been reported previously. The aim of the present study was to determine which characteristics of patients could influence the effectiveness of BOT introduction, and to obtain an equation to estimate HbA1c after BOT initiation. MATERIALS AND METHODS   Sixty consec...

OBJECTIVE We assessed the relationship of mortality with glycated hemoglobin (HbA1c) variability and with absolute change in HbA1c. DESIGN A population-based prospective observational study with a median follow-up time of 6 years. METHODS Based on a validated algorithm, 11 205 Danish individuals with type 2 diabetes during 2001-2006 were identified from public data files, with at least thre...

BACKGROUND The Afinion HbA1c (Axis-Shield) is a newer point-of-care device for measurement of hemoglobin A1c (A1C) using a boronate affinity method unlike the more commonly used DCA immunoassay method (Siemens Medical Solutions Diagnostics). The Afinion's accuracy and precision, when compared with high-performance liquid chromatography (HPLC) and DCA methods, have not been established in pediat...

Background: Diabetic retinopathy is a progressive vision threatening complication of diabetes. Raised plasma level of tumor necrosis factor and other cytokines are accepted as the key in early events in the development of vascular disease. Objective: The aim of this study was to assess the level of some cytokines in diabetic retinopathy and its effect on the severity of diabetic retinopathy. Pa...