Glycyrrhiza uralensis Fisch. is prescribed as one of the original plants licorice in Chinese Pharmacopoeia. This herbal medicine possesses numerous pharmacological activities and has been used clinic China since ancient times. Glycyrrhizic acid (GA) a triterpenoid compound isolated from G. uralensis. It often marker components for medicinal quality herb. Previously, we showed that expression le...

The total number of cumulative cases and deaths from the COVID-19 pandemic caused by SARS-CoV-2 is still increasing worldwide. Although many countries have actively implemented vaccination strategies to curb epidemic, there no specific efficient therapeutic drug for this virus effectively reduce deaths. Therefore, underappreciated macromolecular compounds become spotlight research. Furthermore,...

Induction of growth hormone (GH) by Glycyrrhizae Radix (GR), one of the most popular herbal medicine, and its major ingredients were studied in rat pituitary cells in vitro and in vivo assay. The MeOH extract and the n-hexane (HX) fraction of GR induced rat GH (rGH) release up to 1.89 times (0.34 +/- 0.04 nM) and 4.59 times (0.83 +/- 0.03 nM), compared to the basal level (p < 0.05). Among many ...

The desexycorticosterone-mimetic action of ammoniated glycyrrhizin on electrolyte and water metabolism and on pituitary-adrenal function, was demonstrated in rats. Retention of sodium and water was observed in both intact and adrenalectomized rats during 4 hour minerosteroid assays, the degree of retention being a function of log dose. In intact rats, the antidiuretic effect of glycyrrhizin was...