نتایج جستجو برای: gold nanoshells

تعداد نتایج: 83627  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2003
L R Hirsch R J Stafford J A Bankson S R Sershen B Rivera R E Price J D Hazle N J Halas J L West

Metal nanoshells are a class of nanoparticles with tunable optical resonances. In this article, an application of this technology to thermal ablative therapy for cancer is described. By tuning the nanoshells to strongly absorb light in the near infrared, where optical transmission through tissue is optimal, a distribution of nanoshells at depth in tissue can be used to deliver a therapeutic dos...

Journal: :The Journal of surgical research 2014
Alexander Liberman Zhe Wu Christopher V Barback Robert D Viveros James Wang Lesley G Ellies Robert F Mattrey William C Trogler Andrew C Kummel Sarah L Blair

BACKGROUND High intensity-focused ultrasound (HIFU) is an alterative ablative technique currently being investigated for local treatment of breast cancer and fibroadenomas. Current HIFU therapies require concurrent magnetic resonance imaging monitoring. Biodegradable 500 nm perfluoropentane-filled iron-silica nanoshells have been synthesized as a sensitizing agent for HIFU therapies, which aid ...

Journal: :Optics express 2011
Natalie Garrett Matt Whiteman Julian Moger

Gold nanoshells (GNS) are novel metal nanoparticles exhibiting attractive optical properties which make them highly suitable for biophotonics applications. We present a novel investigation using plasmon-enhanced four wave mixing microscopy combined with coherent anti-Stokes Raman scattering (CARS) microscopy to visualize the distribution of 75 nm radius GNS within live cells. During a laser tol...

Journal: :Journal of biomedical optics 2015
Sergio Sandoval Natalie Mendez Jesus G Alfaro Jian Yang Sharraya Aschemeyer Alex Liberman William C Trogler Andrew C Kummel

A quantification method to measure endocytosis was designed to assess cellular uptake and specificity of a targeting nanoparticle platform. A simple N -hydroxysuccinimide ester conjugation technique to functionalize 100-nm hollow silica nanoshell particles with fluorescent reporter fluorescein isothiocyanate and folate or polyethylene glycol (PEG) was developed. Functionalized nanoshells were c...

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