introduction mycobacterium tuberculosis (mtb) is one of the most common causes of disseminated granulomatous diseases especially in developing countries. case presentation we present a patient who had an unusual type of tuberculosis who was misdiagnosed with some other common diseases such as infective endocarditis and collagen vascular diseases. pathological examination helped us to make decis...

background: mycobacterium marinum infection has a worldwide distribution and the organism occupies many aquatic environments. infections in human consist of nodular cutaneous lesions that can progress to tenosynovitis, arthritis, and osteomyelitis. case presentation: a 27-year-old man was presented with a history of swelling and exudative erythematous lesions and pustules of the right forearm. ...

OBJECTIVES To estimate the prevalence of dyslipidemia (DLP) among individuals with idiopathic granuloma annulare and to examine associations with disease characteristics and comorbidities, such as metabolic syndrome. DESIGN Case-control study using review of medical records from January 2002 through December 2010. SETTING A university hospital and a health care system. PARTICIPANTS Adults...

BACKGROUND The localized form of granuloma annulare is usually self-limiting, resolving within 2 years. Generalized granuloma annulare, on the other hand, runs a protracted course, with spontaneous resolution being rare. It is also characterized by a later age of onset, an increased incidence of diabetes mellitus, poor response to therapy, and an increased prevalence of HLA Bw35. OBJECTIVE To...

The author describes the case of a three-year-old girl presenting with firm, painless retroauricular swelling finally diagnosed as deep granuloma annulare.

Pyogenic Granuloma are benign vascular lesions that occur most commonly on the acral skin and on the oral mucous membrane of children and young adults. The term pyogenic granuloma is a misnomer since it does not produce any purulent secretion, not related to any infection and does not even represent a granuloma histologically. Clinically it appears as pink to red coloured smooth or lobulated ex...

The hallmark of tuberculosis (TB) is the formation of granulomas, which are clusters of infected macrophages surrounded by additional macrophages, neutrophils and lymphocytes. Although it has long been thought that granulomas are beneficial for the host, there is evidence that mycobacteria also promote the formation of these structures. In this study, we aimed to identify new mycobacterial fact...

BACKGROUND In response to Mtb infection, the host remodels the infection foci into a dense mass of cells known as the granuloma. The key objective of the granuloma is to contain the spread of Mtb into uninfected regions of the lung. However, it appears that Mtb has evolved mechanisms to resist killing in the granuloma. Profiling granuloma transcriptome will identify key immune signaling pathway...

1. Burns DA. Necrobiotic disorders. In: Burns T, Breathnach S, Cox NH, Griffiths C, editors. Rook’s text book of dermatology. 8th ed. Oxford: Wiley‐Blackwell; 2010. p. 60.1‐60.12. 2. Garg S, Baveja S. Generalized granuloma annulare treated with monthly rifampicin, ofloxacin, and minocycline combination therapy. Indian J Dermatol2013;58:197‐9. 3. Naveen KN, Pai VV, Athanikar SB, Gupta G, Parshwa...