Background: Granulomatous prostatitis is an uncommon inflammatory process of the prostate, which in most cases, is nonspecific. Clinical presentation, treatment, and evolution are similar to those of benign prostatic hypertrophy, but this lesion is also a clinical mimicker of prostate. Fungal granulomatous prostatitis is rare and there are only a few reported cases. Clinical case: We report the...

OBJECTIVES Report a case of sirolimus induced granulomatous pneumonitis. BACKGROUND Sirolimus is used in clinical transplantation as an immunosuppressive agent. Pulmonary toxicity does occur, but only a few cases of sirolimus associated granulomatous interstitial pneumonitis have been reported. METHODS Case report and literature review. RESULTS This 53-year-old woman with ESRD from polycy...

OBJECTIVES To determine whether cystic neutrophilic granulomatous mastitis (CNGM) can be associated with Gram-positive bacilli and Corynebacterium METHODS We reviewed our experience with 35 granulomatous mastitis patients over a 10-year period, including histologic pattern, Gram stain and other microbiologic data, clinical presentation, treatment and outcome. RESULTS Biopsies from 19 patien...

Hypercalcemia has been widely associated with granulomatous processes. This is due to enhanced extra-renal conversion of calcidiol to calcitriol by activated macrophages within the granuloma. Symptomatic hypercalcemia due to granulomatous disorders is not common, with the incidence in sarcoidosis ranging from 10-20%. Large aggregates of monosodium urate crystals in patients with longstanding ch...

BACKGROUND Granulomatous prostatitis is an uncommon entity that is diagnosed incidentally on histopathology and is broadly classified as nonspecific, specific, postsurgical (post-transurethral resection), or secondary to other rare systemic granulomatous diseases. Only very few studies are available in the literature that describe the clinical and histomorphological spectrum of the disease. M...

A common problem associated with longitudinal studies is the dropouts of subjects or censoring before the end of follow-up. In most existing methods, it is assumed that censoring is noninformative about missed responses. This assumption is crucial to the validity of many statistical procedures. We develop some nonparametric hypothesis testing procedures to test for independent censoring in the ...