background and objectives: kefiran (kef) is a water-soluble polysaccharide that can form transparent film however, it is brittle. therefore, in order to improve the mechanical properties of kefiran film, a mixture with other polymers can be offered. the expansion of mixed systems can propose kefiran and polyvinyl alcohol (pvoh) as a new composite film. materials and methods: solutions of 20 gra...

New computational models of natural site mutations are developed that account for the different selective pressures acting on different locations in the protein. The number of adjustable parameters is greatly reduced by basing the models on the underlying physical-chemical properties of the amino acids. This allows us to use our method on small data sets built of specific protein types. We demo...

Artificial influence: We describe a semi-artificial adenosylpeptide B(12) that behaves as a cofactor in B(12)-dependent enzymatic reactions and demonstrate that the peptide backbone influences its chemical properties and modulates its bioactivity in vitro and in vivo. Inhibition of the growth of L. delbrueckii is demonstrated, thus providing a potentially powerful approach for the development o...

Mesoporous ferrihydrite nanoparticles with incorporated Mn (MMnFh) were prepared for the first time, and MMnFh exhibits excellent performance in removing organic contaminants (CH(3)CHO and toluene) in air. The interesting physico-chemical properties and remarkable activity of MMnFh give great commercial potential in air purification application in diverse sectors.

The present review updates our knowledge about chlorophenols, their chemical reactions and transformations in the natural environment, as well as factors affecting kinetics and mechanisms of these processes. Effects of pH of the environment and structure of molecules (also the number of chlorine atoms and their position in the molecule) on the behaviour of these compounds in the natural environ...

Every technique for toxicity prediction and for the detection of structure-activity relationships relies on the accurate estimation and representation of chemical and toxicologic properties. In this paper we discuss the potential sources of errors associated with the identification of compounds, the representation of their structures, and the calculation of chemical descriptors. It is based on ...

This Account summarizes techniques for fabrication and applications in biomedicine of microfluidic devices fabricated in poly(dimethylsiloxane) (PDMS). The methods and applications described focus on the exploitation of the physical and chemical properties of PDMS in the fabrication or actuation of the devices. Fabrication of channels in PDMS is simple, and it can be used to incorporate other m...