Palmitoylethanolamide (PEA) has antinflammatory and antinociceptive properties widely exploited in veterinary and human medicine, despite its poor pharmacokinetics. Looking for prodrugs that could progressively release PEA to maintain effective plasma concentrations, we prepared carbonates, esters and carbamates at the hydroxyl group of PEA. Chemical stability (pH 7.4) and stability in rat plas...

Phosphoprotein enriched in astrocytes of 15 kDa (PEA-15) binds to extracellular signal-regulated kinase 1 and 2 (ERK1/2) mitogen-activated protein (MAP) kinases to alter ERK1/2 cellular localization and target preferences and binds to adaptors in the extrinsic cell death pathway to block apoptosis. Here, we report that PEA-15 protein expression is inversely correlated with the invasive behavior...

A study to determine the protein digestibility-corrected amino acid score and protein efficiency ratio of nine different cooked Canadian pulse classes was conducted in support of the establishment of protein quality claims in Canada and the United States. Split green and yellow pea, whole green lentil, split red lentil, Kabuli chickpea, navy bean, pinto bean, light red kidney bean, and black be...

Understanding the molecular mechanisms regulating pea seed developmental process is extremely important for pea breeding. In this study, we used high-throughput RNA-Seq and bioinformatics analyses to examine the changes in gene expression during seed development in vegetable pea and grain pea, and compare the gene expression profiles of these two pea types. RNA-Seq generated 18.7 G of raw data,...

Pea (Pisum sativum L.) is an important leguminous plant worldwide, in which pests trigger significant damage every year. One of the most pest pea weevil (Bruchus pisorum, L) causes covert crops. In present study, our aim was to obtain precise information pertaining extent and nature caused by B. pisorum means non-invasive imaging methods. The infested samples were analysed infrared thermometer ...

The small scaffold protein PED/PEA-15 is involved in several different physiologic and pathologic processes, such as cell proliferation and survival, diabetes and cancer. PED/PEA-15 exerts an anti-apoptotic function due to its ability to interfere with both extrinsic and intrinsic apoptotic pathways in different cell types. Recent evidence shows that mice overexpressing PED/PEA-15 present large...

Front-Line Demonstration (FLD) is a long-term educational activity carried out systematically by agricultural experts in the field of farmers to demonstrate value new practices/technologies micro-agriculture situation. The aim FLD was improved pulses technologies for production potential. Improved include use varieties, seed treatment with Rhizobium and PSB culture, sowing methods, balanced fer...

The experiment was conducted for a period of 75 days to study the effect of treatment of straw with urea or with urea and a urease containing chick pea seed meal and midden soil on chemical composition of treated rice straw, feed intake of the animals, nutrients digestibility, body weight gain, and feed conversion efficiency. For the study twelve indigenous growing bulls aged approximately 20 m...

in this study, total factor productivity growth of iran’s pulses (including irrigated pea, dry pea, irrigated lentil, dry lentil, irrigated soybean, dry soybean and irrigated bean) during of farming years 1989-1990 though 2007-2008 had been analyzed, using nonparametric malmquist approach. so, amounts of inputs usages include seeds, fertilizers, dung, poison, herbicide, labor, water and acreage...

Abstract Background In organic crop farms, growing yields are limited by insufficient nitrogen supply to plants and weediness. such legume swards proposed as a service improve cycling. However, positive effect of is not only on cereals but also weeds. rotation, can stimulate the competition using above-ground mass control spread The effects following methods for weeds were analyzed: (i) forage ...