نتایج جستجو برای: gst m1 gst
تعداد نتایج: 25200 فیلتر نتایج به سال:
گلوتاتیون-S-ترنسفرازها (GSTs) آنزیمهایی هستند که در تمامی ارگانیسمهای زنده یافت میشوند و در سمزدایی ترکیبات زنوبیوتیک از طریق فاز II الحاق با گلوتاتیون عمل نموده و نقش مهمی را در مقاومت دارویی ایفا میکنند. فعالیت GST در سویههای مقاوم به کلروکین پلاسمودیوم جوندگان و انسانی به طور معنی داری در مقایسه با سویه های حساس بالاتر میباشد. در مطالعه حاضر فعالیت و سطح GST در موشهای آلوده با پلاسم...
BACKGROUND/AIMS Glutathione S-transferases (GSTs) are cytosolic enzymes excreted from renal tubules following tubular damage. α-GST primarily originates from proximal tubules, while π-GST from distal tubules and collecting ducts. We investigated if GST levels are associated with renal function in patients with type 1 diabetes. METHODS We conducted a cross-sectional study including 189 Caucasi...
BACKGROUND Several assays are used to measure type-specific serological responses to human papillomavirus (HPV), including the bead-based glutathione S-transferase (GST)-L1 multiplex serology assay and virus-like particle (VLP)-based ELISA. We evaluated the high-throughput GST-L1, which is increasingly used in epidemiologic research, as a measure of cumulative HPV infection and future immune pr...
The possible health effects of chronic exposure to petroleum products, in particular exposure to gasoline is an issue of public health concern. Filling station workers are at great risk of exposure to gasoline. To determine the health effects of gasoline exposure on filling station workers, a cross-sectional study was cond...
Gastric stromal tumor (GST) is a set of gastrointestinal mesenchymal tumors those originate from interstitial cells of Cajal. Its early diagnosis and treatment are critical to prognosis.[1] The occurrence of GST remains obscure; this study used Affymetrix expression spectrum chip to detect the gene expression spectrum of GST and explore new molecular target that is used in the treatment and pro...
GST-TAT-SOD, a cell-permeable bifunctional antioxidant enzyme, is a potential selective radioprotector. This study aimed to investigate the cytoprotective activity of GST-TAT-SOD against cisplatin-induced damage. The current study showed that cisplatin induced the formation of reactive oxygen species in normal L-02 cells. GST-TAT-SOD (2000 U/mL) executed its antioxidant role by directly scaveng...
We report that a major 23-kDa allergen from German cockroach (Blattella germanica) is a glutathione S-transferase (EC 2.5.1.18; GST). Natural B. germanica GST, purified from cockroach body extracts by glutathione affinity chromatography, and recombinant protein expressed in Escherichia coli using the pET21a vector, showed excellent IgE antibody binding activity. B. germanica GST caused positive...
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