The lack of homogeneity in field application of Bacillus thuringiensis formulation often results in ingestion of sub-lethal doses of the biopesticide by a fraction of pest population and there by promotes the toxin tolerance and resistance in long term. Gut regeneration seems to be one of the possible mechanism by which this is accomplished. However, the existing information is primarily derive...

Abstract IgA secreting plasma cells (PCs) provide a critical supply of antibodies for barrier functions against pathogens. These express unique tissue-driven transcriptional profiles in their respective niches the bone marrow (BM) and gut. We previously demonstrated that both tissues sustain long-lived IgA+ PCs, but cell intrinsic extrinsic signals responsible survival function gut remain large...

The present study investigated the biodegradation of polystyrene (PS) plastic by mealworm (Tenebrio molitor) on different diets followed untargeted screening larvae gut intestine tissue and frass (manure feed residuals) to investigate existence polymer-generated organic residues. Three diets, consisting PS, rolled barley water were tested. PS degradation rates ranged from 16% 23% within 15 days...

Abstract Tissue-resident memory CD8 +T (T RM) cells are a subset of T positioned at barrier sites, critical for host defense against infection. Recent studies have begun to reveal substantial heterogeneity in RMpopulations across different tissues. The gut consists four anatomically distinct compartments, the epithelia and lamina propria small intestine (siIEL, siLPL) colon (cIEL, cLPL). While ...

Tissue elongation is a fundamental morphogenetic process that generates the proper anatomical topology of the body plan and vital organs. In many elongating embryonic structures, tissue lengthening is driven by Rho family GTPase-mediated cell rearrangement. During this dynamic process, the mechanisms that modulate intercellular adhesion to allow individual cells to change position without compr...

Purpose. Aluminum sucrose octasulfate (SOS) is used clinically to prevent ulcers. Under physiologic conditions, the sodium salt of this drug can be formed. Our objective was to determine whether sodium SOS was absorbed when administered orally. In addition to furthering our understanding of aluminum SOS, this study also aimed to clarify how other polyanionic drugs, such as heparin and lowmolecu...

AIM This study was conducted to evaluate and compare the tissue reactivity and suture handling characteristics of chromic gut, silk, and 'jimat' suture materials in cat thigh muscle. MATERIALS AND METHODS This experimental study was conducted from November, 2013 to April, 2014 in Kombolcha Animal Diseases Survey, Research and Diagnostic Laboratory, Kombolcha, Ethiopia. A total of 36 local bre...

Sucralose is the most widely used artificial sweetener, and its health effects have been highly debated over the years. In particular, previous studies have shown that sucralose consumption can alter the gut microbiota. The gut microbiome plays a key role in processes related to host health, such as food digestion and fermentation, immune cell development, and enteric nervous system regulation....

The Formosan subterranean termite, Coptotermes formosanus Shiraki, is a costly invasive urban pest in warm and humid regions around the world. Feeding workers of the Formosan subterranean termite genetically engineered yeast strains that express synthetic protozoacidal lytic peptides has been shown to kill the cellulose digesting termite gut protozoa, which results in death of the termite colon...

T cells are imprinted to express tissue-specific homing receptors upon activation in tissue-draining lymph nodes, resulting in their migration to the site of Ag entry. Expression of gut-homing molecules alpha(4)beta(7) and CCR9 is induced by retinoic acid, a vitamin A metabolite produced by retinal dehydrogenases, which are specifically expressed in dendritic cells as well as stromal cells in m...