Neuroblastoma-like schwannoma is known as a rare unusual variant of with difficulties differential diagnosis neuroblastoma, Ewing sarcoma/peripheral neuroectodermal tumor and other cutaneous small round cell tumors. Herein, we describe neuroblastoma-like that was presented painless lesion on the dorsal side left hand in 39-year-old woman. Composed collagen fibers central core rosettes diffuse e...

A female, caucasian, 22-year-old patient with no comorbidity, complaining of incapacitating crises of subungual pain in her left hallux, strong enough to wake her up in the middle of the night, starting four years ago, with progressive worsening. The symptom was triggered by a physical stimulus such as cold temperature , local pressure, and even wind causing the crises which improved as she imm...

The cross-reactivity between the tumor-specific trans plantation antigen of tumors induced by adenovirus types 3 and 14, on one hand, and type 12, on the other, was investigated by testing immunosensitivity and immunogenicity. It was found that (a) serum of mice im munized against syngeneic adeno 12 tumors was cytotoxic to hamster adeno 14 and adeno 3 tumor cells, but not to BHK-C13 control cel...

Early-phase clinical development in oncology has evolved dramatically with the deciphering of the human genome in 2004. Genomic analysis and the tools identifying genetically disrupted pathways within a patient's tumor have been a driving force for personalized medicine and for the development of highly targeted novel therapies. Tumors are often genetically heterogeneous, with multiple concurre...

Of primary central nervous system tumors treated each year, the majority are glioma, followed by meningioma and then pituitary adenoma. While the use of magnetic resonance (MR) and computed tomographic imaging is well established in the diagnosis and management of such tumors, these techniques have a limited role in determining the metabolic state, either prior to or following therapy. Multinuc...

Introduction. Primary sarcomas are uncommonly seen in the larynx and comprise around 1% of all laryngeal malignant tumors. We present three cases patients with different types discuss about diagnostic treatment difficulties. Case outline. Each patient presented hoarseness shortness breath. Computed tomography scans showed large transglottic tumors no signs cervical lymphadenopathy definitive di...

Objective Intrauterine sex hormone environment as indicated by the second to the fourth digit ratio (2D : 4D) can be associated with cancer risk. This systematic review and meta-analysis aimed to evaluate the association of 2D : 4D with cancer diagnosis, malignancy, and age at presentation. Methods Studies that evaluated the association of 2D : 4D with cancer risk were collected from Pubmed/M...

BACKGROUND AND PURPOSE Reorganization of brain function may result in preservation of motor function in patients with brain tumors. The goal of the present study was to investigate whether function of the primary motor area (M1) was restored and whether motor function improved after brain tumor resection. METHODS Five patients with metastatic brain tumors located within or near M1 underwent a...

Tumors of the ampulla of Vater can cause symptoms and signs of abdominal pain, jaundice, anemia due to occult gastrointestinal bleeding, recurrent pancreatitis, abnormal liver function tests, biliary or pancreatic duct dilation on imaging studies. Traditional treatments for ampullary tumors are surgical approaches, including transduodenal local resection or pancreaticoduodenectomy (PD). The for...

In medical imaging, segmenting accurately lung tumors stay a quite challenging task when touching directly with healthy tissues. In this paper, we address the problem of extracting interactively these tumors with graph cuts. The originality of this work consists in (1) reducing input graphs to reduce resource consumption when segmenting large volume data and (2) introducing a novel energy formu...