CONTEXT Hepatitis A virus (HAV) infection is an important public health problem. It is estimated that about 1.4 million cases of HAV infection occur every year worldwide. Non-immune healthcare workers (HCWs) can be at higher risk of HAV infection in comparison to general population and an appropriate preventive method should be considered for them. EVIDENCE ACQUISITION For finding related art...

Consumers are driving food production toward the use of natural preservatives and minimal processing technologies. Green tea extract (GTE) at low concentration could be combined with high pressure (HPP) for reduced treatment times quality impact on foods in a hurdle concept synergistic effects foodborne viral pathogens, specifically human norovirus hepatitis A virus (HAV). Viral inactivation by...

This study was undertaken to determine the immune response of humans to viral capsid polypeptides of hepatitis A virus (HAV) after natural infection, which is very important for vaccine development. Antiviral capsids in 73 serum samples from patients with acute and chronic HAV infections were analyzed by immunoblotting against individual HAV capsid polypeptides (VP1, VP2, VP3, and VP4) by using...

The present study pertains to the evaluation of urine as a specimen for detection of anti-hepatitis A virus (anti-HAV) antibodies. Immunoglobulin M (IgM), IgG, and IgA capture enzyme-linked immunosorbent assays for hepatitis A were performed on paired serum and urine specimens collected from hepatitis A patients (n = 92), healthy individuals (n = 100), non-A hepatitis patients (n = 70), and pat...

BACKGROUND We evaluated the recent prevalence of serologic markers of hepatitis A virus (HAV) in South Korea. METHODS The study data were the results of 60 126 anti-HAV (total) tests and 30 786 anti-HAV IgM tests that were performed during April 2009 through March 2010 by the Eone Reference Laboratory at the request of 1935 institutions throughout Korea. RESULTS The overall positivity rate ...

Acute liver failure (ALF) due to hepatitis A virus (HAV) infection is an uncommon but potentially lethal illness. The aim of this study was to identify readily available laboratory and clinical features associated with a poor prognosis among ALF patients with HAV infection. The presenting features of 29 adults with anti-HAV IgM positive ALF enrolled in the ALFSG_between 1998 and 2005 were revie...

Artery Disease To the Editor: We read with great interest the paper by Marek Smieja and colleagues1 showing that exposure to hepatitis A virus (HAV) was not associated with an excess risk of subsequent myocardial infarction, stroke, or cardiovascular death in Heart Outcomes Prevention Evaluation (HOPE) study patients. Total pathogen score based on seropositivity of 4 pathogens (Chlamydia pneumo...

Amaç: Hepatit A, hepatit B, C ve HIV kan vücut sıvılarının bulaşı açısından önde gelen hastalıklardır. Bu çalışmada, sağlık çalışanlarında HAV, HBV, HCV seropozitifliğinin araştırılması amaçlanmıştır.Materyal Metot: Sağlık çalışanlarının serum örneklerinde HBsAg, anti-HBs, anti-HCV, anti-HAV IgG, anti-HBc IgG anti-HIV testleri kemilüminesans esasına dayanan ELISA yöntemi ile çalışıldı.Bulgular:...

Receptor molecules play key roles in the cellular entry of picornaviruses, and TIM1 (HAVCR1) is widely accepted to be the receptor for hepatitis A virus (HAV), an unusual, hepatotropic human picornavirus. However, its identification as the hepatovirus receptor predated the discovery that hepatoviruses undergo nonlytic release from infected cells as membrane-cloaked, quasi-enveloped HAV (eHAV) v...