BACKGROUND The decline in hepatitis B virus surface antigen (HBsAg) may be an early predictor of the viral efficacy of Hepatitis B virus (HBV) therapy. The HBsAg levels obtained by different immunoassays now need comparing and the relationships between levels of HBsAg and HBV DNA alongside HBsAg and genotype must be evaluated. METHODOLOGY/PRINCIPAL FINDINGS HBsAg levels were compared among 80...

The aim of this study was to investigate the relationships between E-selectin +G98T, +A561C polymorphisms and different progression in Hepatitis B virus (HBV) infection Xinjiang Han population, also to determine the HBV DNA copies and pre-S1 antigen (preS1Ag) in this population. Polymorphisms of the E-selectin gene in 200 chronic HBV infection (61 cases of chronic HBV carriers, chronic hepatiti...

The hepatitis B virus (HBV) is the prototype member of a family of hepatotropic DNA viruses, the Hepadnaviridae, that replicate by reverse transcription of an RNA pregenome. HBV infects humans, whereas other hepadnaviruses infect mammals (orthohepadnaviruses) or birds (avihepadnaviruses) (Schaefer, 2007a). HBV comprises eight genotypes (A to H) with distinct virological characteristics and geog...

The Republic of Belarus reports a seroprevalence of 4.8% for hepatitis B virus (HBV) and 1.26% for hepatitis C virus (HCV), but little is known about the molecular characteristics of the circulating viruses. This study analysed 69 HBV surface antigen (HBsAg)-positive and 113 anti-HCV-positive donors attending a national reference hospital in Minsk. Among the HCV patients, 70% were co-infected w...

The hepatitis B virus (HBV) is the prototype member of a family of hepatotropic DNA viruses, the Hepadnaviridae, that replicate by reverse transcription of an RNA pregenome. HBV infects humans, whereas other hepadnaviruses infect mammals (orthohepadnaviruses) or birds (avihepadnaviruses) (Schaefer, 2007a). HBV comprises eight genotypes (A to H) with distinct virological characteristics and geog...

OBJECTIVE The study was designed to assess the hepatitis B virus (HBV) and hepatitis C virus (HCV) co-infection scenario among the human immunodeficiency virus (HIV) infected patients attending a tertiary healthcare unit in eastern India. Additionally, clinical and virological characterization of these viruses, prior to antiretroviral therapy (ART) initiation was also done for better understand...

BACKGROUND Hepatitis B virus (HBV) infection is a major global health problem in the worldwide that associated with significant morbidity and mortality in cardiac surgery. The available data on HBV distribution and genotyping of HBV are very heterogeneous. Therefore in this study, we tried to indicate the prevalence of HBV infections in cardiac catheterization patients referred to health center...

aim : the aim of study was to determine the preliminary result of treatment with pegasys in iranian chronic hepatitis b patients (with genotype d) referred to tehran hepatitis center (thc). background : the genotype of hbv and ethnicity of the patients can affect the response rate to pegasys. patients and methods : during 2006-2008, 12 patients with naïve chronic hepatitis b (genotype d) that r...

An estimated 360 million people are infected with hepatitis B virus (HBV) worldwide. Among these, 65 million live in Africa. Despite the high levels of hepatitis B in Africa, HBV epidemiology is still poorly documented in most African countries. In this work, the epidemiological and molecular characteristics of HBV infection were evaluated among the staff, visitors and adult patients (n = 508) ...

background clinical observations have shown that patients infected with chronic hepatitis b virus (hbv) genotype c versus genotype b had a higher load of the virus, more serious illness, and poorer responses to antiviral therapy and prognosis. however, the disparity between the two has not been clarified. objectives to explore possible relationship between hbv genotypes b and c and peripheral b...