Drug-drug interaction and herb-drug interaction have been frequently reported when patients take propofol in combination with other important clinical drugs or herbs. Intestinal bacteria-catalyzed biotransformation process might significantly change the properties of compounds, such as the efficiency, toxicity, and the pharmacokinetic behaviours. The present study aims to investigate whether th...

Mr J.J., a 32-year-old Iraqi presented for investigation of anhidrosis. In 1967 he first developed a pruritic erythroderma with exfoliation, alopecia, nail loss and mucosal ulceration. There was no history of drug ingestion. Recovery was gradual. Since 1968 the patient has been unable to sweat. As a result he is heat intolerant, with 10 min in a hot environment causing palpitation, headache and...

A few months ago, Murray underwent serious open heart surgery. Unfortunately, all did not go completely smoothly. ButMurray's indominatable spirit helped to pull him through some very tough times. He made use of his love of Mathematics, and throughout this very trying time, he continued to solve problems, pose problems, and make shrewd comments on other people's proposals and solutions. The Edi...

A 52-year-old white man first became ill in September 1968. He was hospitalized at that time at another institution with a right-sided pyopneumothorax treated by thoracotomy with pleural decortication and drainage of the empyema. A lung biopsy was reported as pseudolymphoma. His recovery was uneventful. In October, 1970 he was hospitalized at Hahnemann Medical College and Hospital because of in...

A 43 year old man developed a sudden, severe headache while running in an orienteering competition. He continued to compete for a further 90 minutes before the worsening headache and the onset of vomiting forced him to seek medical help. He had moderate neck stiffness and no neurological deficit when admitted to hospital. Lumbar puncture showed uniformly bloodstained CSF, but CT scan and cerebr...