Detection, localization, and quantification of intracardiac shunts are an integral* part of the hemodynamic evaluation of patients with congenital heart disease. In most cases, an intracardiac shunt is suspected on the basis of the clinical evaluation of the patient before catheterization. There are several circumstances, however, in which data obtained at catheterization should alert the cardi...

Twenty patients with idiopathic hypertrophic subaortic stenosis (IHSS) were studied with cardiac echography. Eight of these patients were studied during left heart catheterization. The echographic pattern of mitral valve motion during systole was altered in a characteristic manner when hemodynamically significant left ventricular outflow obstruction was present in the eight patients studied at ...

Perforation of the heart, which was confirmed by contrast radiography, occurred during venous cardiac catheterization of a dog. As tamponade developed within the next hour, changing physical signs (progressive muffling of heart sounds and murmur, disappearance of a precordial thrill, fall in blood pressure, and increase in heart rate with a weakening pulse) indicated the need for surgical relie...

A 13-year-old boy was admitted for cardiac catheterization because of mitral regurgitation. The family history was noncontributory. He is the second twin, delivered after normal pregnancy without maternal illness, infection, or medication. He showed normal development and weight gain. At the age of 2 years, a heart murmur was first noted; echocardiographically, a small (2.5-mm) ventricular sept...

An unusual case of primary cardiac lymphoma presenting as restrictive cardiomyopathy with arrhythmia is reported in a 72-year-old woman who was admitted for evaluation of exertional dyspnea and palpitations. Electrocardiography (ECG) showed atrioventricular dissociation and right heart cardiac catheterization revealed a typical 'dip-and-plateau' waveform. Restrictive cardiomyopathy was suspecte...

In response to Eduardo Marbán’s invitation to prepare a brief reminiscence on the occasion of the 50th anniversary of Circulation Research, I recount here a few of the ideas and events that have marked my 47 years in research. My research career began when, fresh from a surgical internship at the Johns Hopkins Hospital, I arrived at the then National Heart Institute in 1956. There, having watch...

From 1965 to 1974, 53 children with coarctation of the aorta (COA) and an associated ventricular septal defect (VSD) underwent cardiac catheterization. Thirty-one patients presented with congestive heart failure. Twenty-five of 27 patients (92%) who underwent cardiac catheterization under age 3 months had either systemic hypertension, a systolic gradient across the coarctation greater than 20 m...

We describe a man with the Marfan syndrome and a prior ascending aortic aneurysm resection who presented with knee pain and concern of endocarditis. Transesophageal echocardiogram showed no vegetations, and computed tomography angiogram of the heart showed a possible pseudoaneurysm. Cardiac catheterization and aortogram revealed the diagnosis of an aorto-right atrial fistula, which was then ope...

Simultaneous double vessel acute myocardial infarction (AMI) is extremely rare and usually has poor clinical outcomes. Management of this complicated condition is challenging and time-limited. The case of a 46-year-old Taiwanese man with simultaneous anterior and inferior wall AMI is reported. Rapid deterioration of clinical condition with ventricular fibrillations (VF), cardiogenic shock and a...

Methods After informed consent, 36 patients (age, 45.9 ± 10.1 years; male/female= 25/11, Heart rate=65 ± 8bpm) with chronic thromboembolic pulmonary hypertension (CTEPH) underwent CMRI at 3T (TimTrio, Siemens) and right heart catheterization in the same day. After Four-chamber cine images were acquired during short breath-holds with a retrospectively gated turbo FLASH gradient-echo sequence and...