Heat shock prior, during, or immediately after ionizing radiation synergistically increases cell killing, a phenomenon termed hyperthermic radiosensitization. Recently, we have shown a constitutive DNA-binding factor in rodent cells that is inactivated by heat shock to be identical to Ku autoantigen. Ku, consisting of an Mr 70,000 (Ku70) and an Mr 86,000 (Ku80) subunit, is a heterodimeric nucle...

Metabolic heat production (calculated from oxygen consumption), dry heat loss (measured in a calorimeter) and body temperature (measured by telemetry) were recorded simultaneously at 6 min intervals over five consecutive days in rats maintained in constant darkness. Robust circadian rhythmicity (confirmed by chi square periodogram analysis) was observed in all three variables. The rhythm of hea...

1. Heat loss from three men and three women was measured in a direct calorimeter over 2 or 3 h periods and compared with that determined simultaneously from heat-flow meters attached to the skin surface at the waist. The comparisons were made at each of four ambient temperatures, 15, 20, 25 and 30 degrees. Each subject wore a cotton boiler-suit and minimal underwear. 2. Oral temperatures and sk...

A homeothermic animal maintains a balance between its heat production and the physical processes of heat exchange with its environment by regulating its physiology and behavior. The complexity of heat transfer is beyond comprehension, but the characteristics of heat transfer for different animals in different habitats can be determined through analytical procedures. For example, evaporation los...

BACKGROUND Heat collection rate and heat loss coefficient are crucial indicators for the evaluation of in service water-in-glass evacuated tube solar water heaters. However, the direct determination requires complex detection devices and a series of standard experiments, wasting too much time and manpower. FINDINGS To address this problem, we previously used artificial neural networks and sup...

One of the great enemies of rubber compounds is heat. Heat will cause chemical and physical degradation of vulcanized rubber as well as a considerable loss in its strength. A major source of heat generation in a tire is due to internal friction resulting from the viscoelastic deformation of the tire as it rolls along the road. Another source of heat generation in a tire is due to its contact fr...

The thermoneutral zone is defined as the range of ambient temperatures where the body can maintain its core temperature solely through regulating dry heat loss, i.e., skin blood flow. A living body can only maintain its core temperature when heat production and heat loss are balanced. That means that heat transport from body core to skin must equal heat transport from skin to the environment. T...

A triangular fin with variable fin base thickness is analyzed and optimized using a two-dimensional analytical method. The influence of fin base height and fin base thickness on the temperature in the fin is listed. For the fixed fin volumes, the maximum heat loss, the corresponding optimum fin effectiveness, fin base height and fin tip length as a function of the fin base thickness, convection...