We have demonstrated compression stress induced mechanical deformation of microtubules (MTs) on a two-dimensional elastic medium and investigated the role of compression strain, strain rate, and a MT-associated protein in the deformation of MTs. We show that MTs, supported on a two-dimensional substrate by a MT-associated protein kinesin, undergo buckling when they are subjected to compression ...

Tortuous arteries are often associated with aging, hypertension, atherosclerosis, and degenerative vascular diseases, but the mechanisms are poorly understood. Our recent theoretical analysis suggested that mechanical instability (buckling) may lead to tortuous blood vessels. The objectives of this study were to determine the critical pressure of artery buckling and the effects of elastin degra...

Although buckling instabilities in elastic solids have been known for a long time, high interest in this phenomenon is relatively recent. The current and prospective applications in flexible electronics, materials with tunable surface properties (adhesion and wettability), responsive photonic and phononic structures, and reinforced nanocomposites led to a surge in the interest in buckling insta...

The objective of the present study is to describe the results of research that has been conducted on the buckling behavior of rectangular laminated orthotropic plates that have a rectangular hole. As a result of using some geometrical holes which cause stress concentrations on laminated orthotropic plates, the analysis about the buckling coefficient of the elements become very important. This w...

in this article, surface stress and nonlocal effects on the biaxial and uniaxial buckling of rectangular silver nanoplates embedded in elastic media are investigated using finite difference method (fdm). the uniform temperature change is utilized to study thermal effect. the surface energy effects are taken into account using the gurtin-murdoch’s theory. using the principle of virtual work, the...

An algorithm based on Semi-Definite Programming (SDP) formulation is proposed for optimum design for specified linear buckling load factor. Optimal trusses and frames are computed by using the primal-dual interior-point method for SDP. It is well known that optimizing structures under buckling constraints is difficult because of nondifferentiability of the buckling load factors for the case of ...

We present experiments on the dynamic buckling and fragmentation of slender rods axially impacted by a projectile. By combining the results of Saint-Venant and elastic beam theory, we derive a preferred wavelength lambda for the buckling instability, and experimentally verify the resulting scaling law for a range of materials including teflon, dry pasta, glass, and steel. For brittle materials,...

BACKGROUND Tortuous arteries are often seen in patients with hypertension and atherosclerosis. While the mechanical stress in atherosclerotic plaque under lumen pressure has been studied extensively, the mechanical stability of atherosclerotic arteries and subsequent effect on the plaque stress remain unknown. To this end, we investigated the buckling and post-buckling behavior of model stenoti...

For the first time, we report on methods to control and prevent polymer films from buckling. Buckled morphologies were created by thermally cycling or mechanically compressing a poly(dimethylsiloxane) substrate coated with a polyelectrolyte multilayer film. By variation of the dimensions of the surface topography relative to the buckling wavelength (e.g., pattern size is less than, equal to, an...