OBJECTIVE To determine the efficacy of single doses of albendazole, ivermectin and diethylcarbamazine, and of the combinations albendazole + ivermectin and albendazole + diethylcarbamazine against common intestinal helminthiases caused by Ascaris and Trichuris spp. METHODS In a randomized, placebo-controlled trial, infected children were randomly assigned to treatment with albendazole + place...

در جریان برنامه تحقیقاتی تحت عنوان بررسی رابطه فولیکول چشمی و هلمنتیازیس، بررسی درباره اپیدمیولوژی کرمهای روده ای در مدارس منطقه روستائی اطلاف تهران انجام گرفته است و بطور خلاصه جمعاً مدفوع 944 نفر دانش آموز دبستانی در 6 مدرسه اطراف تهران مورد آزمایش قرار گرفته و بطور متوسط در 2/81 درصد دانش آموزان آلودگی به کرمهای روده ای مشاهده و در آزمایش نوار اسکاچ 8/70 درصد اکسیور و در آزمایش مدفوع 0/29 درص...

Since its initiation in 1995, the African Program for Onchocerciasis Control (APOC) has had a substantial impact on the prevalence and burden of onchocerciasis through annual ivermectin mass treatment. Ivermectin is a broad-spectrum anti-parasitic agent that also has an impact on other co-endemic parasitic infections. In this study, we roughly assessed the additional impact of APOC activities o...

Intestinal helminths and schistosomiasis among school children were investigated in an urban and some rural communities of Ogun State, southwest Nigeria. Fecal samples of 1,059 subjects (524 males, 535 females) aged 3-18 years were examined using direct smear and brine concentration methods between June 2005 and November 2006. The pooled prevalence of infection was 66.2%. Ascaris lumbricoides s...

BACKGROUND Parasitic diseases (eg, malaria and helminthiases) exert enormous burdens on public health and social well-being. Moreover, parasitic infections are important causes of anemia in tropical Africa, exacerbated by lack of a diversified diet and inflammatory and genetic diseases. There is a paucity of longitudinal studies monitoring the dynamics of anemia in relation to the aforementione...

Human toxocariasis is one of the most prevalent helminthiases worldwide. Toxocara canis larvae can cross the blood-brain barrier leading to the neurotoxocariasis. The clinical presentation consists of a wide spectrum of neurological manifestations, but asymptomatic infection is probably common. Neurotoxocariasis is not a frequent diagnosis probably due to the non-specific nature of its symptoms...

BACKGROUND Human dirofilariasis is a zoonotic infection that continues to spread to previously unaffected areas of Europe. In the South Moravian Region of the Czech Republic (CR), imported as well as autochthonous canine infections were recorded in the last decade, and parasite DNA was detected in mosquitoes of Aedes vexans. In the present paper, human Dirofilaria infections are reported from t...

Until the 1960s, the chemotherapy of human intestinal and systemic helminthiases was extremely unsatisfactory;' piperazine compounds, bephenium hydroxynaphthoate and pyrantel embonate were, for example, widely used for the former, and diethylcarbamazine (DEC), niridazole, and bithionol for the latter. Table I summarizes some important agents which have recently become available. The first of th...