The combination of idiopathic pulmonary hemosiderosis (IPH) and celiac disease (CD) is rare. The clinical importance of this association is that a significant improvement can be obtained with gluten free diet not only in intestinal but also in pulmonary symptoms. A four and half-years old girl was admitted with complaints of cough, difficulty in breathing and paleness. She had intermittent epis...

tion in fresh and paraffin-embedded tissue. Clin Chem. 1999;45:573574. 6. Butensky E, Fischer R, Hudes M, et al. Variability in hepatic iron concentration from percutaneous needle biopsy specimens in patients with transfusional hemosiderosis. Am J Clin Path. 2005;123:146-152. 7. Fischer R, Piga A, Harmatz P, Nielsen P. Monitoring long-term efficacy of iron chelation treatment with biomagnetic l...

The clinical course of a 37-year-old white man with idiopathic pulmonary hemosiderosis is presented. This patient is unusual in that he has had repeated exacerbations and remissions over a period of seven years and remains currently in spontaneous remission with no therapy. Routine sections of the lung biopsy revealed characteristec findings. Immunofluorescence staining of the lung was negative...

Idiopathic pulmonary haemosiderosis (IPH) is a rare disorder affecting mainly children and adolescents, and is usually fatal. However, there is increasing evidence that the aetiology of this condition is immunological, and that immunosuppressives may prolong remission. Two cases are reported, one of which has the atypical feature of a malabsorption syndrome. This has not been previously reporte...

The factors which govern the absorption of iron are not well understood. The current theory of iron absorption assigns to bodily need for iron the chief role in the regulation of iron absorption (1, 2). Conclusive evidence is needed, however, to demonstrate the correctness of such a view. In an earlier study from this laboratory (3), it was demonstrated that the high serum iron values and hemos...

Although improvements in the treatment of thalassemia with transfusion and chelation therapy have been achieved, iron overload because of repeated red blood cell transfusions continue to cause organ dysfunction. The prognosis is determined by the degree of involvement of heart disease, mortality in these patients is mainly because of heart failure.1 In this case, cardiac hemosiderosis due to th...

Due to improvements in transfusion therapy in beta-thalassemia major patients, transfusional hemosiderosis has now become the major cause of late morbidity and mortality in them. In India and other developing countries, iron chelation therapy is still not strictly adhered to in these children, mostly due to financial constraints. An orally effective and cheap iron chelator is the need of the ho...