During in vitro fertilization, 22 human embryos were exposed to hepatitis B virus (HBV) in contaminated human serum present in the culture medium. All mothers experienced hepatitis B during the first trimester of pregnancy, and two had hepatitis B surface antigen and HBV DNA, as determined by PCR, at the time of delivery. No HBV DNA was found in serum or lymphocytes from the exposed 22 infants....

Two human hypatitis viruses have been identified and characterized, but one or more additional agents exist. Hepatitis B virus (HBV) is a complex 42-nm predominantly double-stranded DNA virus with distinct surface and core antigens and an endogenous DNA polymerase. Hepatitis A virus (HAV) is a 27-nm RNA virus with enterovirus-like properties. Progressively more sensitive and specific immunologi...

results hepatitis b surface antigen (hbsag) was found in 122/3000 (4.1%) prisoners. hepatitis b e antigen (hbeag), anti-hiv, anti-hcv and anti-hiv/anti-hcv were detected in 52/122 (42.6%), 12/122 (10%), 22/122 (18%) and 3/122 (2.4%) prisoners, respectively. the hbv-dna was found in 115/122 (94.3%) prisoners. the most high risk behavior was to utilize the collaborative syringe by injecting drug ...

Serum and liver tissues from hepatitis B surface antigen-negative/anti-hepatitis C virus (HCV)-negative (non-B, non-C) hepatocellular carcinoma (HCC) patients in Japan were examined for the presence of hepatitis B virus (HBV), HCV, and TT virus (TTV) by polymerase chain reaction. The studies evaluated the contribution of these viruses to pathogenesis of HCC. HBV DNA was detected in the sera of ...

The treatment goal for chronic hepatitis B is true eradication of the hepatitis B virus, but this is rarely achieved with first-line treatment regimens because of an inability to disrupt covalently closed circular DNA and an inadequate host immune response. Therefore, new antiviral agents are needed to target various stages of the hepatitis B virus lifecycle and modulation of the immune system....

Nowadays viral hepatitis is one of the most common and important causes of chronic liver disorders in the world. Extrahepatic manifestations of viral hepatitis consist a main part of the disease. The main viruses causing hepatitis include Hepatitis A, B and C viruses. Herein common skin manifestations in hepatitis C virus (HCV) are discussed. Chronic hepatitis causes skin disorders both directl...

conclusions although hdv had low prevalence in our area, it is vital to plan preventive strategies for hdv spread as well as hbv prevention. it is particularly important to suspect hdv infection in active hbv carriers to manage a particularly severe dual infection. hdv infection should be suspected even in negative hbsag patients having “isolated anti-hbc” profile. results prevalence of hdv was...

INTRODUCTION After the initiation of a mass hepatitis B vaccination program in Taiwan, the prevalence of hepatitis B virus infection has declined progressively. However, about 1 percent of the young generation, who received hepatitis B vaccination at birth, remain carriers. Infection with vaccine-escape hepatitis B virus mutants always occurs shortly after birth. Here, we report two female sibl...

Results The results of this study demonstrate that hepatitis E virus (HEV-RNA) infection to be rare (6.25%) in HBVDNA positive cases. Surface antigen (HBsAg) for hepatitis B virus was positive in 18 cases (45%) and IgM Anti HEV was positive in 16 cases (40%). Hepatitis B virus infections, as the predominant causes of liver diseases, HBV-DNA was detected in 32 cases out of 40 cases and HEV-RNA w...