background hepatitis b virus (hbv) covalently closed circular dna (cccdna) served as a vital role in the life cycle of the virus and persistent infection. however, specific and quantitative methods for cccdna detection have not been available. objectives our aim was to develop and primarily evaluate a quantitative method for hbv cccdna based on magnetic capture hybridization and quantitative pc...

BACKGROUND About ninety percent of immunocompetent adults recover from hepatitis B virus (HBV) infection within 6 months after transmission. The infection is considered to be terminated if the antibodies (HBsAb) to the hepatitis B surface antigen (HBsAg) become detectable and the HBsAg and Hepatitis B virus DNA (HBV DNA,) are no longer perceptible. After recovery from an acute infection, the de...

methods and materials: hepatitis b virus dna was detected by conventional pcr in some of the serum samples obtained from hbsag-positive chronic hepatitis b (chb) patients who were referred to health centers of shahrekord for routine monitoring of the disease. subsequently, using real-time pcr, the dna samples were used for genotyping and analysis of resistance to lamivudine. results: the dna wa...

context since the introduction of highly active anti-retroviral regimen for human immunodeficiency virus-1 infection, a significant increase in the incidence of hepatocellular carcinoma has been reported in patients already chronically infected with hepatitis b virus and then given this form of regimen for their retroviral infection. evidence acquisition this phenomenon was initially attributed...

conclusions although the patients carrying m204i mutation were more likely to show lack of responses to lam therapy, lam replacing by other nucleoside/tide analogs plus hbig maybe still effective in decreasing hepatitis b recurrence after liver transplantation. however, it is suggested that drug resistance test should be considered by clinicians during therapeutic management to avoid the follow...

Background: Infections due to the hepatitis B (HBV) and hepatitis C (HCV) viruses constitute a global public health problem. Although screening of these infections remains a pivotal tool for timely detection and management of carriers, this preventive measure has been neglected in Africa. Objective: The current study determined the prevalence of hepatitis...

hepatitis b infection is the main cause of liver related mortality in many countries including iran. liver transplantation in cirrhosis due to hbv infection before 1990 was an absolute contraindication. recurrent infection was a significant event in post liver transplant setting and resulted in increased risk of graft failure and death except successful transplanted individuals. advances in ant...

results there were 64 women and 936 men in the population under study. the mean ± sd age of the donors was 38 ± 11 years. 80 out of 1000 samples (8%) were found to be positive for hbcab. hbv dna was detected in 50% of hbcab positive specimens. the mean ± sd age of donors without hbv dna was 37.7 ± 10.5 years and for donors with hbv dna was 40.9 ± 11.2 years (p = 0.05). objectives the aim of thi...

Background: Hepatitis is among the major health problems, especially in developing countries. During past decades, the association between type of blood group (ABO) and hepatitis B and C virus has always been discussed. This study was designed to investigate the possible association between type of ABO blood group and chronic hepatitis B and C infection. Methods: In the present analytical stud...

this study was conducted to find out the prevalence, viral load and co-infection of hbv and hcv infection among patients seeking to hospital care in mashhad, iran. a total of 402 samples (349 samples for hbv and 53 for hcv) were received and were screened for hepatitis b and c during 2004 to 2014. viral loads of hbv dna and hcv rna were quantified by real-time pcr. among 349 collected samples, ...