Several viruses have been associated with the development of inflammatory arthritis, including the hepatitis viruses (hepatitis B virus and hepatitis C virus), HIV, the parvovirus B19, the human T-cell lymphotropic virus-I, and the alphaviruses. Here, we review the epidemiology, the pathophysiological mechanisms, the pertinent clinical and laboratory findings as well as the principles of therap...

City-dwelling children from Kenya who were infected with human immunodeficiency virus type 1 (HIV-1) were tested for coinfection with cytomegalovirus (CMV), human T cell lymphotropic viruses 1 and 2, Kaposi sarcoma-associated herpesvirus (KSHV), or hepatitis B, C, and G viruses. All children were found to be coinfected with CMV, whereas 5% had hepatitis G virus coinfection and 15% had KSHV coin...

MicroRNAs (miRNAs) are short sequences of noncoding single-stranded RNAs that exhibit inhibitory effects on complementary target mRNAs. Recently, it has been discovered that certain viruses express their own miRNAs, while other viruses activate the transcription of cellular miRNAs for their own benefit. This review summarizes the viral and/or cellular miRNAs that are transcribed during infectio...

Viruses commandeer regulatory pathways of their hosts to optimize their success as cellular parasites. The human tumor viruses, Epstein-Barr Virus (EBV), Kaposi's Sarcoma Herpesvirus (KSHV), Hepatitis B Virus (HBV), and Hepatitis C Virus (HCV) all affect autophagy for their own ends. EBV and KSHV regulate it during latent infections, a phase when no progeny virus is produced, while HBV and HCV ...

Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections account for a substantial proportion of liver diseases worldwide. Because the two hepatotropic viruses share same modes of transmission, coinfection with the two viruses is not uncommon, especially in areas with a high prevalence of HBV infection and among people at high risk for parenteral infection. Patients with dual HBV and HCV ...

OBJECTIVE To estimate the prevalence of HIV infections, as well as hepatitis B and C and syphilis viruses in homeless people. METHODS Cross-sectional study with educational intervention, conducted in the city of São Paulo, between 2002 and 2003. A convenience sample of homeless people who used night shelters was selected, according to the following criteria: aged 18 or older and not showing p...

introduction:blood-borne infectious agents are one of the main anxieties of blood transfusion organization in all countries. according to who, the blood healthy and blood safety is included ensuring and monitoring of quality and efficiency for all patients requiring blood transfusion. we at the current study intend that survey prevalence hiv ab, hcv ab, hbs ag among blood donors refer to the bl...

The narrow host range of infection and lack of suitable tissue culture systems for the propagation of hepatitis B and C viruses are limitations that have prevented a more thorough understanding of persistent infection and the pathogenesis of chronic liver disease. With hepatitis B virus (HBV), this lack of knowledge has been partially overcome by the discovery and characterization of HBV-like v...

background: microrna is a type of small rna of about 22 nucleotide length. most popular mirnas are found in the liver and are extensively important in determining the biological and clinical functions. microrna, in host cells, may impact the replication of viruses either positively or negatively. in this study the mir-122 expression was examined and compared in three groups, two sample groups o...

It has been a century since the initial discovery of the possible link between viruses and tumors. During the past century, extensive studies have been conducted to understand the relationship between viruses and cancers. The early studies were focused on tumor viruses that do not cause cancers in their natural hosts. These studies provided the basis for the subsequent studies on the six known ...