Splanchnic ischaemia and hepatic dysfunction are severe complications after coronary artery bypass grafting (CABG) and lead to increased morbidity and mortality. Non-invasive determination of the indocyanine green (ICG) plasma disappearance rate (PDR) offers an opportunity for the early diagnosis of hepato-splanchnic hypoperfusion. The aim of this study was to establish the postoperative time c...

Background: The economic cost of and liver and kidney diseases in Sub Saharan Africa remain prohibitive, hence the quest for medicinal foods that can reverse hepato-renal damages. The aim of this study is to investigate the hepato-renal protective effect of wild edible P.tuber-regium on carbon tetrachloride (CCl4) induced oxidative stress in male Sprague–Dawley rats. Method: Thirty six rats wer...

Intraoperative ultrasound examination plays a more and more important role in open or laparoscopic abdominal surgery,satisfying the surgeon's need to correctly characterize lesions,bringing various benefits regarding topography and local regional extension, relations between neighbouring structures and, finally, disease staging. Intraoperative ultrasound is used especially in hepato-bilio-pancr...

PERSPECTIVA INTRODUCTION The Cochrane Hepato-Biliary Group (the CHBG) is a non-profit and not-for-profit independent, international, specialty research group within The Cochrane Collaboration (http://www.cochrane.org). Since its formation in 1996, The CHBG has established itself as a reliable source of evidence-based systematic reviews of interventions within the area of hepato-biliary diseases...

BACKGROUND Activation of the Wnt pathway is known to promote tumorigenesis and tumor metastasis, and targeting Wnt pathway inhibition has emerged as an attractive approach for controlling tumor invasion and metastasis. The major pathway for inhibiting Wnt is through the degradation of β-catenin by the GSK3-beta/CK1/Axin/APC complex. It was found that Hep3B hepato-carcinoma cells respond to anth...

Introduction: This research aimed at evaluating the hepato-protective effect of the alga Spirulina platensis against diclofenac-induced liver injury in rats. The study’s ultimate aim was to understand whether Spirulina could be developed as a functional food for therapy and protective therapeutic use. Methods: Hepatic injury was induced by administering diclofenac sodium (50mg/kg i.p.) for 5 da...

Abstract Green tea or its concentrated extract is coveted for health promoting catechin-like polyphenols, especially epigallocatechin-3-gallate (EGCG). However, amicable efficacy now being doubted considering the recent occurrence of several cases hepato- and nephrotoxicity, after ingestion EGCG-fortified (≥85–90%) nutritional supplements. Therefore, current study was carried out to ascertain e...

Objective: Our study aimed to assess the frequency of PT, outline its clinical and etiological manifestations, detail therapeutic therapy in field hepato-gastroenterology. Study Design: Retrospective Place Duration: In department Medicine Gastroenterology Ayub Teaching Hospital Abbottabad HBS Dental General Hospital, Islamabad for duration six months from June 2021 November 2021. Methods: There...

Abstract: Background: Hepato-Renal impairment refers to renal dysfunction in a liver compromised state concerning lead metal exposure. Natural chelators (marine source) have potent chelating properties claiming ameliorate hepato-renal heavy toxicity Material and Methods: A total of 42 male albino Wistar rats weighing between 200 250 g were categorised into seven groups (n=6). Except for the fir...