نتایج جستجو برای: hepatoma cells
تعداد نتایج: 1385970 فیلتر نتایج به سال:
A biphasic increase of putrescine concentration occurs in rat hepatoma tissue culture cells induced to proliferate. DL-alpha-Methyl ornithine, a competitive inhibitor of ornithine decarboxylase ( L-ornithine carboxylyase, EC 4.1.1.7) of hepatoma tissue culture cells, blocks the usual increases of putrescine and spermidine concentrations in these cells, and causes a rapid fall in the levels of p...
Thyroid hormone (T(3)) signaling through the thyroid hormone receptor (TRα1) regulates hepatoma cell growth and pathophysiology, but the underlying mechanisms are unclear at present. Here, we have shown that the oncomir microRNA-21 (miR-21) is activated by T(3) through a native T(3) response element in the primary miR-21 promoter. Overexpression of miR-21 promoted hepatoma cell migration and in...
INVOLVEMENT OF INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-3 IN THE EFFECTS OF THE HISTONE DEACETYLASE INHIBITOR MS-275 IN HEPATOMA CELLS Wen Hui Lin, Janet L. Martin, Deborah J. Marsh, Michelle M. Jack, and Robert C. Baxter From the Kolling Institute of Medical Research, University of Sydney, and Department of Endocrinology, Royal North Shore Hospital, Sydney NSW 2065, Australia Running head: I...
In Tangier disease, absence of ATP binding cassette transporter A1 (ABCA1) results in reduced plasma HDL and elevated triglyceride (TG) levels. We hypothesized that hepatocyte ABCA1 regulates VLDL TG secretion through nascent HDL production. Silencing of ABCA1 expression in oleate-stimulated rat hepatoma cells resulted in: 1) decreased large nascent HDL (>10 nm diameter) and increased small nas...
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