Citrus fruits contain two groups of flavonoid glycosides that have either rutinose (L-rhamnopyranosyl-ct-1,6-glucopyranoside) or neohesperidose (L-rhamnopyranosyl-:-1.2glucopyranosiele) as their saccharide components. Flavonoid rutinosides such as hesperidin. from mandarin oranges, are tasteless, and on the other hand, flavonoid neohesperidosides such as neohesperidin and naringin, from grapefr...

A one-pot, 2-step flow bioprocess for the obtainment of hesperetin (HP) and quercetin (Q) aglycones from hesperidin (HES) rutin (RT), has been developed, employing a co-immobilized preparation α-rhamnosidase (RN) β-glycosidase (HOR).

The main aim of this study was to investigate the bone-sparing effect of hesperidin, one of the main flavonoid present in oranges, in two age groups of ovariectomized female rats, compared with their intact controls. Young (3 mo) and adult (6 mo) female Wistar rats were sham operated (SH) or ovariectomized (OVX) and then pair-fed for 90 days a casein-based diet supplemented or not with 0.5% hes...

Experimental protocols and functional studies: All animal procedures were approved by the Animal Studies Subcommittee (IACUC) of the San Francisco Veterans Administration Medical Center and performed in accordance with their guidelines. Since hesperidin is not soluble in 100% ethanol, 70% ethanol was used as vehicle. Since the turnover time for hairless is about 8-9.5 days in normal young mice ...

Objectives: The study is planned to investigate the antidiabetic activity of hesperidin on Streptozotocin (STZ)-induced diabetes mellitus in Swiss Albino mice. Materials and Methods: mice were divided into six groups viz., normal control, diabetic insulin 0.75 IU/kg, 100, 200 400 mg/kg, respectively (n = 6/group). All received treatments once daily for 21 consecutive days, except control groups...

More and more research is being focused on the production of value-adding products from waste materials. Food not only a major global issue, but also an excellent source bioactive compounds. In this study, parameters that affect extraction compounds (polyphenols, ascorbic acid, hesperidin, carotenoids) orange peels, their antioxidant properties, were optimized, using response surface methodolog...