نتایج جستجو برای: high dose interferon
تعداد نتایج: 2344472 فیلتر نتایج به سال:
The protection and immune response to infection caused by the parasite Schistosoma mansoni were studied by comparison of two murine irradiated-vaccine models. Mice were exposed from 1 to 4 times to infective-stage cercariae attenuated with either a moderate dose (15 kilorads) or a high dose (50 kilorads) of radiation. Seven weeks after challenge infection, the mice were assessed for resistance,...
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The time-sequential change in immune-related gene expression of the glioblastoma cell line after irradiation was evaluated to speculate effect combined immunotherapy with radiotherapy. U373 MG irradiated 6 Gy single dose. Next-generation sequencing (NGS) transcriptome data generated before (control), and at 6, 24, 48 h post-irradiation. Immune-related pathways were analyzed each time period. sa...
OBJECTIVE To describe current management of cutaneous melanoma (CM) and identify factors accounting for disparities. DESIGN Retrospective population-based study using survey of cancer registries and pathology laboratories, and questionnaires to physicians. SETTING Five regions covering 19.2% of the French territory and including 8.2 million inhabitants. PATIENTS Incident cases of patients...
A significant proportion of patients with chronic hepatitis C virus (HCV) infection who undergo antiviral therapy have persistent or recurrent viremia and fail to achieve a sustained virologic response (SVR). Factors associated with treatment failure include HCV genotype 1 infection, high serum HCV RNA levels, and advanced fibrosis. Consensus interferon (CIFN) is a synthetic type I interferon d...
AIM Real-world data on treatment patterns/outcomes in patients with advanced melanoma, while scarce, are useful for health technology assessments that govern patient access in many countries. We collected retrospective data on treatment patterns among patients in France, Germany and the UK with Stage IIIB/IIIC melanoma with macroscopic lymph node involvement, whose primary melanoma and regional...
In a double-blind placebo-controlled study a preparation of human leucocyte interferon purified by affinity chromatography using a monoclonal antibody and applied by repeated nasal sprays reduced the incidence and severity of colds in volunteers challenged with human rhinovirus 9. Although interferon itself caused some symptoms, these were minor compared with the clinical colds. Interferon acti...
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