Long term survival of NSC lung cancer relies on successful surgical resection. However, approximately 75% of primary lung carcinoma cases present with surgically incurable disease and are treated with alternative approaches such as radiation and/or chemotherapy. The survival results are however poor. About 50-60% of patients treated with external radiation therapy will experience local recurren...

PURPOSE Peri-urethral cancer (PUC) in females is a rare malignancy. Surgery is not usually contemplated due to associated morbidity. Radiation therapy (RT) can be employed in the form of interstitial brachytherapy (IBT) alone for early lesions, and external beam radiation therapy (EBRT) with or without IBT for advanced lesions. We report our first experience in the literature to evaluate the ro...

OBJECTIVE To compare the inverse planning optimization based on total dose constraints versus conventional treatment plan (point A planning method) for cervical carcinoma, and evaluate the benefit of CT-based image-guided brachytherapy. METHODS We prospectively analyzed data of 10 consecutive patients with cervical cancer treated with external beam radiotherapy to the whole pelvis (45 Gy in 2...

Interstitial brachytherapy represents the treatment of choice for small tumours, regionally localized in the oral cavity and the oropharynx. In the technical setting, continuous low-dose-rate (LDR) brachytherapy represented for many years the gold standard for administering radiation in head and neck brachytherapy. Large series of head and neck cancer patients treated with LDR brachytherapy hav...

PURPOSE The aim of this paper is to report the treatment of angiosarcoma of the scalp. High-dose-rate (HDR) brachytherapy with an individual mold applicator is presented. CASE DESCRIPTION A case of a 75-year-old male will be presented with multicentric lesions over the scalp in the temple and crown region. Biopsy diagnosis was angiosarcoma of the scalp, nonoperable. The patient was qualified ...

Introduction: Long-term teletherapy program is not suitable for old and working patients and those living in areas where little access to primary health care is available. Accelerated partial breast irradiation (APBI) using high dose rate (HDR) brachytherapy is an appropriate alternative for these patients due to its limited number of fractions. The AccuBoost is a system for delivering APBI. Th...

BACKGROUND Low-dose rate brachytherapy is a well established treatment modality of oral cancer. Data about high-dose rate (HDR) brachytherapy are still sparse with various fractionation schedules and heterogeneous results. AIM The aim of our retrospective study was to evaluate the results of HDR brachytherapy with doses of 3 Gy twice daily. PATIENTS AND METHODS Twenty patients with squamous...

Background: For an effective treatment planning in brachytherapy, it is necessary to know the accurate source dosimetric information such as air kerma strength, exposure rate constant, dose rate constant and redial dose distribution. The usual method to determine these factors is thermo luminescent dosimeter (TLD) dosimetry. Nowadays, another more accurate method is known to be the Monte Carlo ...

background: iodine brachytherapy sources with low photon energies have been widely used in treating cancerous tumors. dosimetric parameters of brachytherapy sources should be determined according to aapm tg-43u1 recommendations before clinical use. monte carlo codes are reliable tools in calculation of these parameters for brachytherapy sources. materials and methods: dosimetric parameters (dos...

Pulsed Dose Rate (PDR) treatment is a new brachytherapy modality that combines physical advantages of high-dose-rate (HDR) technology (isodose optimization and radiation safety) with radiobiological advantages of low-dose-rate (LDR) brachytherapy. Pulsed brachytherapy uses a stronger radiation source than that employed in LDR brachytherapy and provides a series of short 10 to 30 minutes long ex...