BACKGROUND The aim of this study was to evaluate matrix tablets containing different ratios of Carbopol(®) 971P (CP) to low-viscosity sodium alginate (SA) and assess their suitability for pH-independent controlled drug release. METHODS Two processing methods (physical mixing, PM and spray-drying, SD) were applied before compaction and the release from corresponding matrices was compared. The ...

*Research Scholar Department of Pharmacy, School of Medical and Allied Sciences Galgotias University, Gautam Buddh Nagar, Greater Noida (U.P.) e-mail: [email protected] Abstract: The objective of the present study was to develop floating microspheres of Gliclazide in order to achieve an extended retention in the upper gastrointestinal tract, which may result in enhanced absorption a...

BACKGROUND Several new measures based on the regularity of the electroencephalogram signal for the assessment of depth of anesthesia/sedation have been proposed recently. In this study we analyze the influence of remifentanil and electroencephalogram frequency content of the performance of a set of such measures. METHODS Forty-five patients with American Society of Anesthesiologists physical ...

Introduction: Eggshell membrane (ESM) is a tissue found between the eggshell and albumen of eggs that has attractive properties for use in drug delivery systems. Aim: To incorporate ESM used it as model release studies. The color change FTIR analysis biopolymer proved incorporation nimesulide ESM. Results: uptake was 176.83 122.69 mg g-1 by natural cross-linked Release studies were carried out ...

In this study, the effects of various hydrophilic (HPMC and Carbopol 971) and plastic (Ethylcellulose and Eudragit RL100) polymers on the release profile of diltiazem HCl from matrix tablets were evaluated in-vitro. For this purpose, tablets containing 60 mg of diltiazem HCl along with various amounts of the aforementioned polymers were prepared using the wet granulation technique. Tablets prep...

Aim : This study was aimed to formulate a transdermal matrix patch using green tea leaf extract. Materials and methods The formulation optimized by the simplex lattice design method. correlation between responses analyzed chemometrics. observed were: 1. physical properties of patch, 2. percentage dissolution efficiency catechins, caffeine, epigallocatechin gallate released from patch. determina...

Despite extensive research on the taxonomy and phylogeny of subfamily Aphidiinae Haliday, 1833, certain questions about relationships between genera remain unresolved. Genera Trioxys 1833 Binodoxys Mackauer, 1960 are considered closely related, based morphological molecular analyses. However, recent studies suggest there is a need for taxonomic revision two genera, since data does not support m...

Using the model for the processive movement of a dimeric kinesin we proposed before, we study the dynamics of a number of mutant homodimeric and heterodimeric kinesins that were constructed by Kaseda et al. (Kaseda, K., Higuchi, H. & Hirose, K. (2002) PNAS 99, 16058–16063). The theoretical results of ATPase rate per head, moving velocity, and stall force of the motors show good agreement with t...

Emotion recognition from EEG could be used in many applications as it allows us to know the “inner” emotion regardless of the human facial expression, behaviour, or verbal communication. In this paper, we proposed and described a novel fractal dimension (FD) based emotion recognition algorithm using an Arousal-Valence emotion model. FD values calculated from the EEG signal recorded from the cor...

The goal of the present investigation was to design and evaluate mucoadhesive buccal patches of Cyproheptadine Hydrochloride (CPH) which is a sedating antihistamine with antimuscarinic, serotonin-antagonist, and calcium-channel blocking action. Buccal films were made with Hydroxy propylcellulose (HPC EF) and Hydroxy Propyl Methyl Cellulose (HPMC E15) as mucoadhesive polymers. Permeation of CPH ...