BACKGROUND Ischemia reperfusion (I/R) is common in various pathological conditions like diabetic complication, rheumatic arthritis, necrotizing vascular occlusive disease and trauma. METHODS We have evaluated the effect of tacrolimus (1, 2 and 3 mg/kg, p.o. for 10 consecutive days) on femoral arterial ischemic reperfusion (I/R) induced neuropathic pain in rats. Behavioral parameters (i.e. hot...

Methimazole is the most widely prescribed antithyroid medication in humans. However, hepatotoxicity is a deleterious adverse effect associated with methimazole administration. No specific protective agent has been developed against this complication yet. This study was designed to investigate the role of taurine as a hepatoprotective agent against methimazole-induced liver injury in mice. Diffe...

BACKGROUND The authors report a case of fibrous encapsulation of the peritoneal catheter, which caused peritoneal shunt malfunction, and has not previously been researched well as a complication of peritoneal shunts. CASE DESCRIPTION A 69-year-old woman who had undergone a lumboperitoneal (LP) shunt for communicative hydrocephalus following subarachnoid hemorrhage caused by a ruptured aneurys...

BACKGROUND AND AIM Transjugular liver biopsy is accepted procedure in patients in whom percutaneous liver biopsy is contraindicated. We report our experience with this procedure, its indications, efficacy and safety in Indian population over 5 years. MATERIAL & METHODS A retrospective study of 145 consecutive patients who had undergone transjugular liver biopsy from May 2002 to Nov. 2007 was ...

background: diabetes mellitus is associated with cognitive deficits in humans and animals. these deficits are paralleled by neurophysiological and structural changes in brain. in diabetic animals, impairments of spatial learning, memory, and cognition occur in association with distinct changes in hippocampus, a key brain area for many forms of learning and memory and are particularly sensitive ...

this study was done to determine whether high or low dose of anti-snake venom (asv) is better in coagulopathy in victims of envenoming by vipers. this retrospective study was conducted on the 154 patients (mean age ± sd, range) of viper snake bites who were referred to the emergency ward of razi hospital, ahvaz, iran over 2 years period (2004 - 2006). according to the treatment dosage the patie...

background: a rare and devastating complication following anterior cruciate ligament (acl) revision reconstruction is femoral fracture.    case presentation: a 35-year old male soccer player with a history of acl tear from the previous year ago, who underwent arthroscopic acl reconstruction and functioned well until another similar injury caused acl re-rupture. revision of acl reconstruction wa...

STUDY DESIGN Retrospective cohort study. OBJECTIVE The objective of the study was to determine rates of medical and surgical postoperative complications following anterior lumbar interbody fusion (ALIF) along with their associated predictors. METHODS Using the American College of Surgeons National Surgical Quality Improvement database, patients who underwent single-level ALIF surgery from 2...

Recessive dystrophic epidermolysis bullosa (RDEB) is a severe hereditary skin disease characterized by and mucosa fragility with blister formation due to type VII collagen deficiency. The major complication in RDEB patients the development of squamous cell carcinoma (SCC) leading premature mortality. Our study aims correlate immune profiles SCCs clinico-histopathological features cohort patient...

The breakage of an epidural catheter, which is usually not noticed, is a rare but important complication encountered while inserting or removing the catheter during epidural blockade. While the epidural catheter was being inserted for labor analgesia, despite no problem being encountered in advancing the catheter, it was drawn back to verify the location; it was observed that 2 cm of the distal...