The bovine MHC (BoLA) class II DRB3 alleles are associated with polyclonal expansion of lymphocytes caused by bovine leukemia virus (BLV) infection in cattle. To examine whether the DRB3*0902 allele, one of the resistance-associated alleles, is associated with the proviral load, we measured BLV proviral load of BLV-infected cattle and clarified their DRB3 alleles. Fifty-seven animals with DRB3*...

India is the foremost milk producing nation of the world, and homes the largest domesticated bovine population. But the average productivity of indigenous/non-descript animals is far below than that of Taurine cattle. Crossbreeding of low producing indigenous and nondescript cattle with high producing exotic breeds like Holstein Friesian and Jersey is followed as the breeding policy of the coun...

Bovine Leucocyte Adhesion Deficiency (BLAD) is a Holstein-Friesian HF) specific autosomal recessively inherited disorder characterized by recurrent pneumonia, ulcerative and granulomatous stomatitis, enteritis, periodontitis, loss of teeth, delayed wound healing, persistent neutrophilia and death at an early age [1]. BLAD is a disease characterized by a reduced expression of the adhesion molecu...

Electrocardiograms were recorded from 89 clinically healthy Holstein cattle divided into 10 age groups, comprising newborn calves (18 to 72 hours), 15 days, 1, 3, 6 and 9 months and 1, 3, 5, and 7 years of age. The electrocardiograms were recorded on a bipolar base apex lead, using limb lead I. Duration and amplitude of the P, QRS complexes, T waves and the PR, RR, QT and ST intervals were meas...

By means of discriminant analysis, it can be identified which class the individuals (data) desired to classified. In this study, was aimed identify that milk samples belong breed, applying analysis taken from cattle breeds (19 heads Jersey, 53 Holstein and 27 Charolaise) in first lactation. As a conclusion proper classification actualized rate, considered quite high like 90.6%, according compon...

To investigate the genetic basis of hereditary lens opacities we analyzed 31 cases of bilateral congenital cataract in Red Holstein Friesian cattle. A genome-wide association study revealed a significant association on bovine chromosome 7 at positions 6,166,179 and 12,429,691. Whole genome re-sequencing of one case and four relatives showed a nonsense mutation (g.5995966C>T) in the PZP-like, al...

The study was carried out on eight Bos indicus cattle breeds namely, Sahiwal, Tharparkar, Nimari, Khilari, Deoni, Amritmahal, Hariana and Hilly cattle; two Bos taurus cattle breeds namely, Jersey and Holstein Friesian and Indicine×Taurine crossbred cattle to find out the polymorphic pattern of beta-lactoglobulin gene. The polymorphism at beta-lactoglobulin gene was detected by conducting PCR-RF...

Many studies suggest significant genetic variation in the resistance of cattle and humans to infection with Mycobacterium bovis, the causative agent of zoonotic tuberculosis. The inducible nitric oxide synthase (iNOS which is encoded by the NOS2 gene) plays a key role in the immunological control of a broad spectrum of infectious agents. This study aimed to investigate the influence of genetic ...

As a complement to the Bovine HapMap Consortium project, we initiated a systematic study of the copy numbervariation (CNV) within the same cattle population using array comparative genomic hybridization (array CGH). Oligonucleotide CGH arrays were designed and fabricated to cover all chromosomes with an average interval of 6 kb using the latest bovine genome assembly. In the initial screening, ...

Many studies suggest significant genetic variation in the resistance of cattle and humans to infection with Mycobacterium bovis (M. bovis), the causative agent of zoonotic tuberculosis. TNF-α promotes inflammation and induces apoptosis in response to mycobacterial infection. The aim of the present study was to investigate the influence of single nucleotide polymorphisms of the TNF-α gene on bov...