BACKGROUND The aim of the study was to determine the effect of postmenopausal hormone therapy on women's symptom reporting and quality of life in a randomized trial. METHODS 1823 women participated in the Estonian Postmenopausal Hormone Therapy (EPHT) Trial between 1999 and 2004. Women were randomized to open-label continuous combined hormone therapy or no treatment, or to blind hormone thera...

The issue of hormone therapy for transgender inmates, while seemingly limited in importance, is one that involves issues of greater importance for the transgender community. The greatest issue at the heart of the matter is the legal argument that is traditionally used to gain access to hormone therapy: the Eighth Amendment. The Eighth Amendment prohibits deliberate indifference to the medical n...

Menopause is diagnosed after 12 months of amenorrhoea resulting from the permanent cessation of ovarian function. The mean age at menopause is 51 years. The perimenopause, a time of changing ovarian function, precedes the final menses by several years. The physiology and clinical manifestations of this transition to menopause are not well understood; however, some symptoms, such as hot flashes,...

OBJECTIVE To test whether estrogen receptor polymorphisms modify the effects of postmenopausal hormone therapy on biomarkers and on risk of coronary heart disease events, stroke, or venous thromboembolism. METHODS AND RESULTS The design was a nested case-control study in the Women's Health Initiative trials of postmenopausal hormone therapy. The study included all cases in the first 4 years: ...

BACKGROUND Some studies of premenopausal women suggest that the severity of psychopathology associated with schizophrenia may be related to levels of estrogen. METHODS We examined psychopathology in community-dwelling postmenopausal women with schizophrenia who had received (n = 24) versus had never received (n = 28) hormone replacement therapy. RESULTS Users of hormone replacement therapy ...

T he termination of the estrogen-progestogen trial of the Women’s Health Initiative (WHI) study in July 2002 was a milestone in the history of postmenopausal hormone therapy. In response, The North American Menopause Society (NAMS) convened an expert Hormone Therapy (HT) Advisory Panel to prepare a report on hormone therapy. After approval from the 2001-2002 NAMS Board of Trustees, the report w...

Hypothyroidism was the first endocrine disorder treated by replacement with the deficient hormone, in the form of extracts of animal thyroid glands. Subsequently, the development of purified thyroid hormone preparations and greater understanding of thyroid physiology have made it possible to mimic the function of the normal thyroid gland with thyroid hormone replacement therapy. Thyroid hormone...

Prostate cancer is the most common in men Poland. The choice of treatment method depends on many factors, including stage disease, patient's age, life expectancy, presence comorbidities and general condition patient. Hormone therapy one basic methods prostate treatment, both adjuvant palliative treatment. Castration-resistant an incurable disease. However, introduction new hormonal drugs to sig...

to evaluate the effectiveness of conjugated estrogen (premarin) and progesterone in twenty-one postmenopausal women who had been menopause one year, we tested during a 6-month period the serum lipoprotein levels in subjects who offered by premarin in dosage of 0.625 milligram for days 1 to 25 and oral medroxy progestrone acetste for days 15 to 25 of a 30-day cycle. twenty-one subjects completed...

OBJECTIVE The terms "natural" or "bioidentical" hormone therapy (NHT) are used to describe hormone treatment with individually compounded recipes of certain steroids in various dosage forms, including dehydroepiandrosterone, pregnenolone, testosterone, progesterone, estrone, estradiol, and estriol. Based on the results of a person's salivary hormone levels, the final composition of the compound...