Urinary Tract Infections (UTI) is one of the most common infections, especially among women. Presently accessible antibiotics are a clinician’s first line defense to treat but antimicrobial resistance menace reduce their efficacy. The consequences multi-drug enhanced morbidity and mortality rates. yearly death toll >700,000 population worldwide, rising ~10 million by 2050. There lack novel f...

Acinetobacter species are associated with high mortality, A. baumannii being a significant number of hospitals acquired infections worldwide. Multidrug resistance makes it challenging to control or treat these infections. Aim this study is evaluate the risk factors and compare clinical outcomes in tertiary care hospital, COVID non patients.

BACKGROUND Gram-negative bacterial bloodstream infection (BSI) is a serious condition with estimated 30% mortality. Clinical outcomes for patients with severe infections improve when antibiotics are appropriately chosen and given early. The objective of this study was to estimate the association of prior healthcare exposure on time to appropriate antibiotic therapy in patients with gram-negativ...

Telavancin is a lipoglycopeptide that has activity against Gram-positive aerobic and anaerobic bacteria. It has activity against methicillin-resistant Staphylococcus aureus, vancomycin-intermediate S. aureus and non-Van-A strains of vancomycin-resistant enterococci. It has been approved by the US Food and Drug Administration (FDA) for complicated skin and skin structure infections and hospital-...

background: recently the role of platelets in the tissue regeneration, wound healing and prevention and control of infections has been reported. we aimed to assess the antimicrobial effect of human platelet concentrate against six bacteria, commonly found in wound and hospital-acquired infections. methods: in vitro susceptibility to samples of 10 random human platelet concentrates was determine...

Intensive care unit (ICU)-acquired infections as a result of multidrug-resistant Gram-negative pathogens remain a serious problem in critically ill patients. Adult ICU patients who received intravenous fosfomycin were prospectively examined to assess its safety and effectiveness as an adjunct to the antimicrobial therapy of life-threatening infections caused by carbapenem-resistant Klebsiella p...