background: the role of diagnostic pathology has become more prominent. this study aimed to compare the accuracy of frozen section compared with permanent section in the morning and afternoon working hours. methods: in this cross-sectional study, 99 patients with stage 1 and 2 breast cancer who underwent sentinel and non-sentinel lymph node biopsy between 2013 and 2015 were included. the result...

Background: Preeclampsia is a serious complication of pregnancy, and it is vital to diagnosis the condition as early as possible. Proteinuria is an important symptom of preeclampsia, and repeated urine analysis to screen for the condition is part of the standard antenatal care. The purpose of this study was to determine the correlation between 4- and 24-hour urine total protein values to examin...

Abstract Background Extremity replantation as well allotransplantation aim to restore form and function of the amputated limb. Both approaches, however, are clearly limited by ischemic time. Ex vivo perfusion (EVP), already well-established in field solid organ transplantation, represents a promising tool overcome this restriction. Methods We have currently established technical requirements pr...

objective: both the length of extra-alveolar time and type of storage media are significant factors that can affect the long-term prognosis of replanted teeth. this study aims to compare propolis 50%, propolis 10%, hank’s balanced salt solution (hbss), milk and egg white on periodontal ligament (pdl) cell survival for different time points. materials and methods: in this in vitro experimental s...

Ethylene oxide was tested on groups of rats for either 4-hour or 1-hour inhalation exposure, followed by 14 days of observation. Groups of five Sprague-Dawley rats/sex were exposed, and clinical signs and mortality were recorded. Clinical signs noted included irregular breathing, absence of certain reflexes, and tremors. Rats that died had moderate to severe pulmonary congestion. The calculated...

OBJECTIVES Shiftwork is now a major feature of working life across a broad range of industries. The features of the shift systems operated can impact on the wellbeing, performance, and sleep of shiftworkers. This paper reviews the current state of knowledge on one major characteristic of shift rotas-namely, shift duration. Evidence comparing the relative effects of eight hour and 12 hour shifts...

The present study was conducted to compare the pharmacokinetics and pharmacodynamics (PD) of paclitaxel between Phase I trials of 3- and 24-h infusions and to determine the most informative pharmacokinetic parameter to describe the PD. Twenty-seven patients were treated in a Phase I study of paclitaxel by a 3-h infusion at one of six doses: 105, 135, 180, 210, 240, and 270 mg/m2. Pharmacokineti...