Dipeptidyl peptidase 4 (DPP4), a transmembrane protein, has been identified in human adipose tissue and is considered to be associated with obesity-related type 2 diabetes. Since adipose tissue is relatively hypoxic in obese participants, we investigated the expression of DPP4 in human preadipocytes (hPA) and adipocytes in hypoxia, during differentiation and upon insulin stimulation. The result...

In this paper, we propose four parallel algorithms (NPA, SPA, HPA and HPA-ELD) for mining association rules on shared-nothing parallel machines to improve its performance. In NPA, candidate itemsets are just copied amongst all the processors, which can lead to memory over ow for large transaction databases. The remaining three algorithms partition the candidate itemsets over the processors. If ...

OBJECTIVE This study explored the physico-chemical properties of late-incubation egg amniotic fluid and a potential in ovo feed (IOF) supplement. METHODS Amniotic fluid was collected from broiler breeders (Ross 308, 51 weeks and Cobb 500, 35 weeks) on day 17 after incubation. A mixture of high-quality soy protein supplement - Hamlet Protein AviStart (HPA) was serially diluted in MilliQ water ...

Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a severe disease that is caused by maternal alloantibodies generated during pregnancy or at delivery as a result of incompatibility between maternal and fetal human platelet antigens (HPAs) inherited from the father. Antibody-mediated immune suppression using anti-HPA-1a immunoglobulins is thought to be able to prevent FNAIT caused by HP...

BACKGROUND Neonatal alloimmune thrombocytopenia (NAIT), caused by maternal antibodies raised against alloantigens carried on foetal platelets, is a very common haematological abnormality in newborns worldwide. However, baseline data on NAIT in China are lacking. Therefore, this study seeks to explore the incidence of alloantibody against the human platelet antigen (HPA) in pregnant women and it...

This study finds an increasing trend in the decay timescale (τ) of western North Pacific (WNP) tropical cyclone (TCs) making landfall on Asian continent from 1966–2018. Statistical analysis individual landfalling TCs shows that τ is significantly positively linked to soil wetness, 850-hPa relative vorticity and 200-hPa divergence, whereas it weakly correlated with 700–500-hPa humidity 850–200-h...

[1] We examined the consistency of time series for stratospheric ozone obtained by ozonesondes, SAGE II, HALOE, and SBUV(/2) in the northern extratropics and find excellent agreement for interannual variability and trends of ozone for 50–12.5 hPa over Europe. Ozonesonde, SAGE, and HALOE data agree well for 200 hPa–12.5 hPa. Ozone in the past few years is 6% below values in the early 1980s for 8...

Scheff JD, Calvano SE, Lowry SF, Androulakis IP. Transcriptional implications of ultradian glucocorticoid secretion in homeostasis and in the acute stress response. Physiol Genomics 44: 121–129, 2012. First published November 29, 2011; doi:10.1152/physiolgenomics.00128.2011.— Endogenous glucocorticoids are secreted by the hypothalamicpituitary-adrenal (HPA) axis in response to a wide range of s...

Under normal conditions, the adrenal glucocorticoids, the endproduct of the hypothalamic-pituitary-adrenal (HPA) axis, provide a frontline of defence against threats to homeostasis (i.e. stress). On the other hand, chronic HPA drive and glucocorticoid hypersecretion have been implicated in the pathogenesis of several forms of systemic, neurodegenerative and affective disorders. The HPA axis is ...

Dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis influences the risk for developing stress-related disorders. Sex-dependent differences in the HPA axis stress response are believed to contribute to the different prevalence rates of stress-related disorders found in men and women. However, studies examining the HPA axis stress response have shown mixed support for sex differences, ...