نتایج جستجو برای: hpv 18
تعداد نتایج: 366353 فیلتر نتایج به سال:
BACKGROUND Human papillomaviruses (HPV) have been considered to be the necessary and central agents of cervical carcinoma. OBJECTIVE The aim of this study was to determine the prevalence and genotypes of HPV in archival cervical carcinomas. STUDY DESIGN The study included 152 paraffin-embedded, formaldehyde-fixed cervical carcinoma specimens. To improve the detection and typing of HPV in ar...
BACKGROUND Both cervical cancer and human immunodeficiency virus (HIV) are major public health problems in Sub-Saharan Africa. The objectives of the study were to investigate human papillomavirus (HPV) prevalence according to age, HIV status and gender. METHODS Participants were 208 HIV-negative women, 278 HIV-positive women, 325 HIV-negative men and 161 HIV-positive men between the ages of 1...
BACKGROUND Human papilloma virus (HPV) infection was the main cause of cervical cancer. There were only a few reports and detailed data about epidemiological research of HPV infection in rural population of China. MATERIALS AND METHODS The cervical cells of rural Chaozhou women were collected, and multiplex real time PCR was firstly performed to detect high-risk HPV (HR-HPV) infection, which ...
日本は子宮頸がん検診の受診率が約40％で、HPVワクチン接種率は約1％であり、若年者の子宮頸癌が増加傾向にある。未受診者対策としての自己採取HPV検査の精度について検討した。2012年の自己採取器具Delphi（wet法）によるPCR法HPV検査での検討では、CIN2＋（20例）のHPV検査陽性率（感度）は自己採取90％（18/20）、医師採取85％（17/20）であった。2013年の自己採取器具Evalyn brush（dry法）によるPCR法HPV検査での検討では、CIN2＋（20例）のHPV検査陽性率は自己採取90％（18/20）、医師採取90％（18/20）であった。2014年の自己採取器具Flocked Swabs（dry法）によるPCR法HPV検査では、CIN2＋（21例）のHPV検査陽性率は、自己採取100％（21/21）、医師採取95％（20/21）であった。2016...
Introduction: Cervical screening programmes differ in the age of women recommended for primary human papillomavirus (HPV) testing. This study aims to determine clinical efficacy and impact 14-high-risk HPV DNA testing from 25 years old. Method: was a retrospective analysis data collected prospectively or older who attended hospital-based gynaecology clinics cervical screening. Women with histor...
The human papillomavirus type 18 (HPV-18) upstream regulatory region (URR) controls cell type-specific expression of viral oncoproteins E6 and E7. The HPV-18 URR is highly active in HeLa cells, but its activity is virtually undetectable in HepG2 cells. Previous work has shown that YY1 plays an important role in activation of the HPV-18 URR in HeLa cells, and this activating activity is dependen...
In this retrospective study, we investigated the HPV DNA occurrence in 21 laryngeal and 26 primary lung squamous cell carcinomas. Nonisotopic in situ hybridization (NISH) technique was performed with commercially available digoxigenin-labelled DNA probes for HPV screening. Subtyping for HPV subtypes 6/11, 16/18 and 31/33 was also performed. We observed HPV DNA signals in 10 (47.6%) cases of lar...
The pathogenesis of endocervical glandular lesions are not clearly understood. The aims of this study are to evaluate the etiologic role of human papillomavirus (HPV) 16/18 and the relationship of HPV 16/18, p53 and MIB-1 expressions in endocervical glandular dysplasia (EGD), adenocarcinoma in situ (AIS) and adenocarcinoma. The materials included 14 endocervical adenocarcinoma and 5 AIS and 18 ...
BACKGROUND In recent years, efforts have been made to identify molecular markers as potential screening tools in the early detection of cervical cancer precursors. PATIENTS AND METHODS One-hundred-eighty-two women admitted to the Colposcopy Unit of Tor Vergata University Hospital were enrolled in this study. The inclusion criteria were: i) Pap test with atypical squamous cells of undetermined...
PURPOSE Persistent infections by high-risk human papillomavirus (HPV) types are the main etiologic factor for cervical cancer. The objective of this study was to evaluate whether high-risk E7 oncoprotein is adequate as a marker for the detection of cervical cancer. EXPERIMENTAL DESIGN HPV typing was done in biopsies from 58 cervical carcinoma and 22 normal cervical squamous epithelia. The HPV...
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