Insulin-like growth factors (IGF) are known paracrine/autocrine regulators of ovarian development in teleosts. Initial studies investigated the hormonal and intracellular signal cascades involved in regulating the expression of ovarian-derived IGFs in zebrafish (Danio rerio). Quantitative real-time PCR was used to quantify the expression of igf3, igf2a, and igf2b in full grown immature (FG; 0.5...

A negative urine pregnancy test in the emergency department traditionally excludes the diagnosis of pregnancy. We report a rare case of ruptured ectopic pregnancy in a patient with a negative urine pregnancy test but with a serum beta-human chorionic gonadotropin (β-hCG) of 10 mIU/mL. The patient developed hemoperitoneum and required laparoscopy by Obstetrics and Gynecology (OB/Gyn). This case ...

Qualitative and quantitative serum human chorionic gonadotropin (hCG) tests are used to diagnose pregnancy. We assessed physicians' perceptions and compared turnaround times (TATs) and performance characteristics of both tests. We surveyed 1,058 physicians about their perceptions of hCG tests. Seven months of TAT data were analyzed. hCG was measured in all qualitative samples. Pregnancy status ...

Since it was first claimed in 1995 that human chorionic gonadotropin (hCG) inhibits HIV-associated Kaposi's sarcoma (KS), focus has been lost on establishing a credible hypothesis to explain a novel action ascribed to hCG, which is, after all, a pregnancy hormone. After 7 years, no real progress has been made, and there remains no consensus as to which component of hCG preparations is responsib...

Background To assess the usefulness of premature luteinization hormone (LH) surge prevention in an intrauterine insemination (IUI) cycle by GnRH antagonist administration MaterialsAndMethods Sixty patients with unexplained or mild male infertility or minimal to mild endometriosis were enrolled in this prospective randomized controlled trial. There were twenty patients in group A (with GnRH anta...

Although it is clear that human chorionic gonadotropin (hCG) and progesterone play fundamental roles in pregnancy, the regulation of placental production of these hormones remains to be defined. Recent evidence suggests that the human placenta expresses proteins related to inhibin (alpha beta subunits) or activin (beta beta subunits). Inhibin and activin (follicle-stimulating hormone-releasing ...

A 26-year-old woman at 7 weeks and 4 days of gestation presented with atypical vaginal bleeding mild abdominal pain. Transvaginal ultrasound revealed a free hypoechoic area 10 mm in the pouch Douglas 13-mm thick homogenous endometrium no evidence gestational sac. mass (46 × 38 mm) was detected outside uterine fundus. T1-weighted MRI performed, revealing 4-cm between left side fundus ovary. Labo...

CONTEXT AND OBJECTIVE In men with infertility secondary to gonadotropin deficiency, treatment with relatively high dosages of human chorionic gonadotropin (hCG) stimulates intratesticular testosterone (IT-T) biosynthesis and spermatogenesis. Previously we found that lower dosages of hCG stimulated IT-T to normal. However, the minimal dose of hCG needed to stimulate IT-T and the dose-response re...

25 Although color Doppler ultrasonography has been used to evaluate testicular blood flow in 26 many species, very little has been done in goat. Eight male Shiba goats were exposed to a 27 single intramuscular injection of either gonadotropin-releasing hormone (GnRH group; 28 1μg/kg BW) or human chorionic gonadotropin (hCG group; 25 IU/kg BW). Plasma 29 testosterone (T), estradiol (E2), and inh...

Within the last year, human chorionic gonadotropin (hCG) has been a topic of great discussion in both the scientific and popular press. Recent reports have demonstrated that because of hCG’s heterogeneity, assay standardization is an important problem, with different immunoassays giving different results for the same specimens. In addition there have been reports of falsenegative results due to...