Participants in prolonged, physically demanding cold-weather activities are at risk for a condition called "thermoregulatory fatigue". During cold exposure, the increased gradient favoring body heat loss to the environment is opposed by physiological responses and clothing and behavioral strategies that conserve body heat stores to defend body temperature. The primary human physiological respon...

Evidence-Based Answer No recent evidence demonstrates that methylphenidate improves fatigue in patients receiving palliative care. Methylphenidate can be used to minimally improve fatigue symptom scores in patients with cancer-related fatigue. (Strength of Recommendation [SOR]: C, based on a meta-analysis of multiple randomized controlled trials [RCTs] with heterogeneous results.) Methylphenida...

The paper deals with evaluation of reliability of a human operator in the MMS (Man-MachineSystem). In terms of controls the driver is a very universal and effective controller. In contrast to an unnatural controller the driver fatigue (both mental and physical) is reflected and it is reduces driver control abilities. The paper describes analyzing of driver trajectory and driver ́s state monitori...

background: fatigue, depression, and physical impairment are common  among  multiple  sclerosis (ms) patients. the aim  of  this  study was to  determine  the   relationship between depression,  physical impairment,  and  fatigue  in an iranian ms cohort. methods: fifty consecutive  relapsing-remitting ms patients and  50 age- and  sex-matched healthy  controls (hcs) were recruited  from sina r...

Fatigue in operational settings has many facets, as is discussed in various other contributions in this volume. One of the most pervasive manifestations of fatigue in today’s 24/7 economy is in the form of human impairment resulting from extended work hours and night and shift work. Such work schedules lead to sleep insufficiency and temporal misalignment relative to the biological clock (i.e.,...

Fatigue is one of the most common and distressing side effects of cancer and its treatment, and may persist for years after treatment completion in otherwise healthy survivors. Guided by basic research on neuro-immune interactions, a growing body of research has examined the hypothesis that cancer-related fatigue is driven by activation of the pro-inflammatory cytokine network. In this review, ...

Vertebral fractures associated with osteoporosis are often the result of tissue damage accumulated over time. Microscopic tissue damage (microdamage) generated in vivo is believed to be a mechanically relevant aspect of bone quality that may contribute to fracture risk. Although the presence of microdamage in bone tissue has been documented, the relationship between loading, microdamage accumul...

Multimodal learning is an expanding research area and aims to pursue a better understanding of given data by regarding different modals. approaches for qualitative are used the quantitative proofing ground-truth datasets discovering unexpected phenomena. In this paper, we investigate effect multimodal schemes assess its state. We try interpret human fatigue levels through analyzing video, therm...

Cyclic stresses are often related to the premature mechanical failure of metallic biomaterials. The complex interaction between fatigue and corrosion in the physiological environment has been subject of many investigations. In this context, microstructure, heat treatments, plastic deformation, surface finishing and coatings have decisive influence on the mechanisms of fatigue crack nucleation a...

Introduction Fatigue may contribute to the human error component of medical errors. Hospitals function around the clock, which necessitates shift work for many personnel. Physicians, especially those in training, typically work long hours and are often sleep deprived. Personnel who work during evenings and at night experience disruptions in circadian rhythms, which may aggravate fatigue. Althou...