Abstract Human cytomegalovirus (CMV) causes severe disease in immunocompromised individuals. CMV-based vectors are promising candidates vaccination and immunotherapy approaches. Here, we report on our approach to make chimpanzee CMV (CCMV) available for research vector development. We cloned the CCMV genome created a global picture of infection program by multi-omics. Via engineering distinct r...

background :  sequence-based identification of various microorganisms including archaea, bacteria, cyanobacteria, diatoms, fungi, and green algae necessitates an efficient and reproducible genome extraction procedure though which a pure template dna is yielded and it can be used in polymerase chain reactions (pcr). considering the fact that dna extraction from these microorganisms is time consu...

mitochondrial deoxyribonucleic acid (mtdna) polymorphisms were examinedin bone samples of individuals buried inan early neolithic (c. 5800–4900 bce) hunter-gatherer cemetery, shamanka ii, located atthe southwestern tip of lake baikal, siberia. the mainobjective was to compare the mtdna polymorphisms observed at shamanka ii to those previously reportedfrom the lokomotiv (early neolithic) and ust...

Age-associated changes in the DNA methylation state can be used to assess pace of aging. However, it is not understood what mechanisms drive these and whether affect development aging phenotypes process general. This study was aimed at gaining a more comprehensive understanding aging-related across whole genome, relating biological functions. It has been shown that skeletal muscle blood monocyt...