نتایج جستجو برای: human leukocyte antigen hla

تعداد نتایج: 1824505  

Journal: :Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2008
Andri Rauch David Nolan Hansjakob Furrer Elizabeth McKinnon Mina John Simon Mallal Silvana Gaudieri Huldrych F Günthard Patrick Schmid Manuel Battegay Bernard Hirschel Amalio Telenti Ian James

We assessed the influence of human leukocyte antigen (HLA) alleles HLA-Bw4 and HLA-Bw6 on CD4 T cell recovery after starting successful combination antiretroviral therapy in 265 individuals. The median gains in the CD4 T cell count after 4 years were 258 cells/microL for HLA-Bw4 homozygotes, 321 cells/microL for HLA-Bw4/Bw6 heterozygotes, and 363 cells/microL for HLA-Bw6 homozygotes (P = .01, c...

Journal: :Viral immunology 2011
Sheng-Fan Wang Kuan-Hsuan Chen Marcelo Chen Wen-Yi Li Yen-Ju Chen Ching-Han Tsao Muh-yong Yen Jason C Huang Yi-Ming Arthur Chen

One-hundred and thirty confirmed cases of severe acute respiratory syndrome (SARS) were recruited to evaluate their anti-SARS-coronavirus (CoV) antibody status and human leukocyte antigen (HLA) types in September 2006, 3 y after the SARS outbreaks in Taiwan. Western blot assay showed that 6.9% of participants still had anti-spike and anti-nucleocapside antibodies. A case-control study of the as...

2017
Daniela Maira Cardozo Amanda Vansan Marangon Ana Maria Sell Jeane Eliete Laguila Visentainer Carmino Antonio de Souza

The Human Leukocyte Antigen (HLA) system is the Major Histocompatibility Complex (MHC) in humans, and all knowledge on this system is of great interest to the field of medical sciences. HLA has become an important tool for understanding the pathogenesis of various infectious diseases; the alleles or HLA haplotypes inherited by an individual can predict several risk and protective factors relate...

Journal: :Iranian journal of allergy, asthma, and immunology 2015
Hamid Nawaz-Tipu

The object of this cross sectional study was to determine the HCV subtype 3a envelope protein binding affinity with Human Leukocyte Antigen. Envelope 1 (E1) protein is one of the structural proteins responsible for entering the cells through the receptors. The binding affinity of E1 protein epitopes to the selected Human Leukocyte Antigen (HLA) class I alleles was investigated using the compute...

Journal: :BMC Bioinformatics 2021

Abstract Background Accurate prediction of binding between class I human leukocyte antigen (HLA) and neoepitope is critical for target identification within personalized T-cell based immunotherapy. Many recent tools developed upon the deep learning algorithms mass spectrometry data have indeed showed improvement on average predicting power HLA-peptide interaction. However, their performances sh...

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