rabbits have the capacity to regenerate holes in their ears by forming a blastema, a tissue that is made up of a group of undifferentiated cells. the purpose of the present study was to isolate and characterize blastema progenitor cells and compare them with marrow mesenchymal stem cells (mscs). five new zealand white male rabbits were used in the present study. a 2-mm hole was created in the a...

conclusions according to the results of the present study, it can be concluded that adipose derived mscs can be cultured in serum-free media with no change in their differentiating capacity. this finding gives us a hope for future cell therapy studies and trials with little concern about zoonotic infections or immunological reaction. results the isolated cells showed adherent spindle shaped mor...

introduction: failure of human body tissue and organs is believed to be one of the most important health problems all over the world. the great challenge for tissue engineers is to optimize suitable systems to separate, proliferate and differentiate the cells so that they can set out to create tissue by a harmonic 3-d growth. therefore, the tissue engineers must provide an environment like the ...

introduction: various neuroregenerative procedures have been recently employed along with neurorehabilitation programs to promote neurological function after spinal cord injury (sci), and recently most of them have focused on the acute stage of spinal cord injury. in this report, we present a case of acute sci treated with neuroprotective treatments in conjunction with conventional rehabilitati...

The melanoma cell adhesion molecule defines mesenchymal stromal cells in the human bone marrow that regenerate bone and establish a hematopoietic microenvironment in vivo. The role of the melanoma cell adhesion molecule in primary human mesenchymal stromal cells and the maintenance of hematopoietic stem and progenitor cells during ex vivo culture has not yet been demonstrated. We applied RNA in...

background infertility is a serious social problem in advanced nations, with male factor in half of all cases of infertility. this study was conducted to determine the regenerative effect of bone marrow-derived stem cells in spermatogenesis of infertile hamster. methods twelve adult male hamsters were equally divided into azoospermic and control groups. busulfan was intraperitoneally used for i...

objective(s):in previous investigations, we have shown para-nonylphenol (p-np) caused significant reduction of proliferation and differentiation of rat bone marrow mesenchymal stem cells (mscs) in vitro. in this study, we first treat the rats with p-np, then carried out the biochemical and morphological studies on mscs. materials and methods: proliferation property of cells was evaluated with t...

objective(s): mesenchyme is a type of undifferentiated loose connective tissue that is derived mostly from mesoderm. recently, mesenchymal stem cells (mscs), as adult stem cells (ascs) able to divide into a variety of different cells, are of utmost importance for stem cell research. in this research, ability of the liver extract to induce differentiation of rat derived omentum tissue mesenchyma...

  Introduction: The field of stem cell biology and regenerative medicine is rapidly moving toward translation to clinical practice. Stem cell therapy seems to be a new treatment option for some diseases. So, tracking the distribution of stem cells is crucial to their therapeutic use. Based on this fact we labeled human mesenchymal stem cells (MSCs) with 111...